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https://doi.org/10.1016/S0021-9150(97)00180-9
DC Field | Value | |
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dc.title | Cardiovascular risk factors in non-insulin-dependent diabetics compared to non-diabetic controls: A population-based survey among Asians in Singapore | |
dc.contributor.author | Hughes, K. | |
dc.contributor.author | Ong, C.-N. | |
dc.contributor.author | Choo, M. | |
dc.contributor.author | Kuperan, P. | |
dc.contributor.author | Aw, T.-C. | |
dc.date.accessioned | 2012-04-02T07:02:24Z | |
dc.date.available | 2012-04-02T07:02:24Z | |
dc.date.issued | 1998 | |
dc.identifier.citation | Hughes, K., Ong, C.-N., Choo, M., Kuperan, P., Aw, T.-C. (1998). Cardiovascular risk factors in non-insulin-dependent diabetics compared to non-diabetic controls: A population-based survey among Asians in Singapore. Atherosclerosis 136 (1) : 25-31. ScholarBank@NUS Repository. https://doi.org/10.1016/S0021-9150(97)00180-9 | |
dc.identifier.issn | 00219150 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/32000 | |
dc.description.abstract | Cardiovascular risk factors were compared between 126 people with non- insulin-dependent diabetes mellitus (NIDDM) and 530 non-diabetics (controls), in a random sample of people (Chinese, Malays, and Asian Indians) aged 40-69 years from the general population of Singapore. Data were adjusted for age and ethnicity. For both genders, people with NIDDM had higher mean body mass indices, waist-hip ratios and abdominal diameters. They also had a higher prevalence of hypertension, higher mean levels of fasting serum triglyceride, slightly lower mean levels of serum high-density-lipoprotein cholesterol, and higher mean levels of plasma plasminogen activator inhibitor-1 and tissue plasminogen activator (antigen). These factors are components of syndrome X (metabolic syndrome) and increase the risk of atherosclerosis and thrombosis. In contrast, there were no important differences for cigarette smoking, serum total and low-density-lipoprotein cholesterol, serum apolipoproteins A1 and B, plasma factor VIIc and plasma prothrombin fragment 1 + 2. Females with NIDDM, but not males, had a higher mean serum fibrinogen level than non- diabetics, which could explain why NIDDM has a greater cardiovascular effect in females than males. Serum lipoprotein(a) concentrations were lower in people with NIDDM. Mean levels of serum ferritin, a pro-oxidant, were higher in people with NIDDM than controls, but there were no important differences for plasma vitamins A, C and E, and serum selenium, which are anti-oxidants. | |
dc.description.uri | http://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/S0021-9150(97)00180-9 | |
dc.source | Scopus | |
dc.subject | Anti- oxidants | |
dc.subject | Atherosclerosis | |
dc.subject | Haemostasis | |
dc.subject | Lipids | |
dc.subject | Lipoproteins | |
dc.subject | Obesity | |
dc.subject | Pro-oxidants | |
dc.type | Article | |
dc.contributor.department | COMMUNITY,OCCUPATIONAL & FAMILY MEDICINE | |
dc.contributor.department | MEDICINE | |
dc.contributor.department | PATHOLOGY | |
dc.description.doi | 10.1016/S0021-9150(97)00180-9 | |
dc.description.sourcetitle | Atherosclerosis | |
dc.description.volume | 136 | |
dc.description.issue | 1 | |
dc.description.page | 25-31 | |
dc.description.coden | ATHSB | |
dc.identifier.isiut | 000072378900004 | |
Appears in Collections: | Staff Publications |
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