Please use this identifier to cite or link to this item: https://doi.org/10.1016/S0378-4274(99)00081-8
DC FieldValue
dc.titleReference values and action levels of biological monitoring in occupational exposure
dc.contributor.authorOng, C.N.
dc.date.accessioned2012-04-02T06:56:30Z
dc.date.available2012-04-02T06:56:30Z
dc.date.issued1999
dc.identifier.citationOng, C.N. (1999). Reference values and action levels of biological monitoring in occupational exposure. Toxicology Letters 108 (2-3) : 127-135. ScholarBank@NUS Repository. https://doi.org/10.1016/S0378-4274(99)00081-8
dc.identifier.issn03784274
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/31957
dc.description.abstractThe primary objectives of biological monitoring are (1) to prevent health impairment, (2) to assist in the assessment of risk, and (3) to evaluate the effectiveness of environmental controls. An efficient way to achieve these objectives would be to enforce the compliance of biological exposure standards at the workplace. However, biological monitoring should be viewed in the total context of control and prevention of work-related diseases, and not merely to comply with permissible standards. Biological monitoring depends very much on the conditions that the chemical is absorbed and how it is metabolised. Genetic diversity could therefore contribute to significant differences in this aspect. Furthermore, many of the reference values established have so far not been fully validated and therefore their usefulness is rather limited. This paper reviews and illustrates using some recent findings to show that biological reference values are influenced not just by the above mentioned issues, but also factors such as (1) health and nutritional status of the exposed population, (2) social and cultural factors, and (3) climatic conditions. Caution has to be taken when considering having an action level for some of the biological reference value. Biological reference values set without considering people, technology, and working conditions would be fraught with difficulties in implementation.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/S0378-4274(99)00081-8
dc.sourceScopus
dc.subjectBiomarkers
dc.subjectMetabolism
dc.subjectThreshold limit values
dc.subjectToxicity
dc.typeReview
dc.contributor.departmentCOMMUNITY,OCCUPATIONAL & FAMILY MEDICINE
dc.description.doi10.1016/S0378-4274(99)00081-8
dc.description.sourcetitleToxicology Letters
dc.description.volume108
dc.description.issue2-3
dc.description.page127-135
dc.description.codenTOLED
dc.identifier.isiut000082792900006
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

9
checked on May 4, 2021

WEB OF SCIENCETM
Citations

6
checked on Apr 27, 2021

Page view(s)

211
checked on May 6, 2021

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.