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Title: Effects of kainate on glucose metabolising enzymes in the brain
Authors: Leong, S.F. 
Issue Date: 1991
Citation: Leong, S.F. (1991). Effects of kainate on glucose metabolising enzymes in the brain. Life Sciences 48 (6) : 561-567. ScholarBank@NUS Repository.
Abstract: Hexokinase and glucose-6-phosphate dehydrogenase activities were studied in brain regions after intraventricular injection of kainic acid. Hexokinase activity was decreased by 10-15% in various regions while glucose-6-phosphate dehydrogenase activity remained unaltered. Soluble hexokinase activity, which remained the smaller fraction of total hexokinase activity, showed slightly more dramatic decreases of 15-35% compared to normal activities in brain regions. This decrease of hexokinase activity in the cytosolic compartment could partly account for the kainate-induced decreases seen in glucose metabolism.
Source Title: Life Sciences
ISSN: 00243205
DOI: 10.1016/0024-3205(91)90471-M
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