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Title: Medication use and retinal vessel diameters
Authors: Wong, T.Y. 
Knudtson, M.D.
Klein, B.E.K.
Klein, R.
Hubbard, L.D.
Issue Date: 2005
Citation: Wong, T.Y., Knudtson, M.D., Klein, B.E.K., Klein, R., Hubbard, L.D. (2005). Medication use and retinal vessel diameters. American Journal of Ophthalmology 139 (2) : 373-375. ScholarBank@NUS Repository.
Abstract: Purpose: To study the influence of different medications on retinal vessel diameters. Design: Cross-sectional study. Methods: Retinal photographs in the Beaver Dam Eye Study (n = 4926, aged 43 to 84 years) were digitized, and the diameters of retinal vessels were measured. Participants' current medications were recorded at the examination. Results: There were few significant associations between medication use and retinal vessel diameters. After adjusting for age, blood pressure, and other factors, participants who were using topical beta-blocker eyedrops had narrower retinal arteriolar (P = .05) and venular (P = .006) diameters than nonusers. Systemic beta-blocker was not associated with retinal vessel diameter size. Conclusion: We found few associations between current medication use and retinal vessel diameter. Retinal vessels were narrowed in those taking antiglaucoma medications, most strikingly in those prescribed topical beta-blockers, although such a relationship could not be established among those using systemic beta-blockers. © 2005 by Elsevier Inc. All rights reserved.
Source Title: American Journal of Ophthalmology
ISSN: 00029394
DOI: 10.1016/j.ajo.2004.08.008
Appears in Collections:Staff Publications

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