Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.chemphys.2005.09.044
Title: Single stranded DNA stabilization and assembly of Au nanoparticles of different sizes
Authors: Yang, J.
Lee, J.Y. 
Too, H.-P. 
Chow, G.-M. 
Gan, L.M.
Keywords: Assembly
Au nanoparticles
Hybridization
Single stranded DNA
Issue Date: 2006
Citation: Yang, J., Lee, J.Y., Too, H.-P., Chow, G.-M., Gan, L.M. (2006). Single stranded DNA stabilization and assembly of Au nanoparticles of different sizes. Chemical Physics 323 (2-3) : 304-312. ScholarBank@NUS Repository. https://doi.org/10.1016/j.chemphys.2005.09.044
Abstract: The binding affinity of single stranded DNA (ssDNA) for Au nanoparticles was found to be strongly size dependent. The data clearly indicate that the interaction is not due to a charge screening effect. The smaller particles (5 nm) showed the most pronounced effect and inhibited the hybridization of complementary DNA sequences adsorbed on the Au nanoparticle surface. An experimental procedure was subsequently developed to allow the assembly of 17 and 5 nm gold nanoparticles using only single stranded DNA without the need for DNA hybridization. The assembly was confirmed by transmission electron microscopy (TEM). A potential pitfall in using DNA melting point analysis to infer metal nanoparticle assembly by DNA hybridization was also discovered during the development of this experimental procedure. © 2005 Elsevier B.V. All rights reserved.
Source Title: Chemical Physics
URI: http://scholarbank.nus.edu.sg/handle/10635/28920
ISSN: 03010104
DOI: 10.1016/j.chemphys.2005.09.044
Appears in Collections:Staff Publications

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