Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.jns.2008.08.001
DC FieldValue
dc.titleA rare cause of reversible unilateral third nerve palsy
dc.contributor.authorLui, N.-L.
dc.contributor.authorThumboo, J.
dc.contributor.authorSee, S.-J.
dc.date.accessioned2011-09-27T05:14:55Z
dc.date.available2011-09-27T05:14:55Z
dc.date.issued2008
dc.identifier.citationLui, N.-L., Thumboo, J., See, S.-J. (2008). A rare cause of reversible unilateral third nerve palsy. Journal of the Neurological Sciences 275 (1-2) : 188-190. ScholarBank@NUS Repository. https://doi.org/10.1016/j.jns.2008.08.001
dc.identifier.issn0022510X
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/26718
dc.description.abstractCase report: A 59-year-old Chinese male presented in January 2007 with acute left retro-orbital headache, diplopia and left partial ptosis. Isolated left third nerve palsy was diagnosed. Imaging studies and cerebral angiography excluded a posterior communicating artery aneurysm. Anti-nuclear (titre 1/800, speckled pattern), anti-PR3, anti-Ro and anti-La antibodies were present. Sjogren's syndrome (SS) was considered in view of positive anti-Ro and La antibodies, and was confirmed with focal lymphocytic infiltrates on labial salivary gland biopsy and a positive Schirmer's test (6 mm of tear flow over 5 min). Immunosuppressive therapy was started 2 months after his initial presentation and within 2 weeks, the patient experienced an almost complete recovery of both ptosis and diplopia. He has been on tapering doses of prednisolone since and his condition remains stable. Conclusion: This patient has cranial neuropathy secondary to Sjogren's syndrome. The rapid reversibility of the oculomotor nerve palsy with immunosuppression suggests lymphocytic infiltration or autoantibodies as the cause rather than a vasculitic process, which would have led to irreversible or slowly, partially reversible ischaemic damage. © 2008 Elsevier B.V. All rights reserved.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.jns.2008.08.001
dc.sourceScopus
dc.subjectCranial nerve disease
dc.subjectSjogren's syndrome
dc.subjectVasculitis
dc.typeArticle
dc.contributor.departmentMEDICINE
dc.description.doi10.1016/j.jns.2008.08.001
dc.description.sourcetitleJournal of the Neurological Sciences
dc.description.volume275
dc.description.issue1-2
dc.description.page188-190
dc.identifier.isiut000261749100038
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