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Title: Nocistatin attenuated the nociceptin induced c-Fos expression in the mouse hippocampus
Authors: Kazi, J.A. 
Liu, E.H.C. 
Lee, T.L. 
Tachibana, S. 
Keywords: c-Fos
Issue Date: 2007
Citation: Kazi, J.A., Liu, E.H.C., Lee, T.L., Tachibana, S. (2007). Nocistatin attenuated the nociceptin induced c-Fos expression in the mouse hippocampus. Neuropeptides 41 (4) : 227-231. ScholarBank@NUS Repository.
Abstract: Nocistatin and nociceptin/orphaninFQ (N/OFQ) are the two new peptides which may have roles in nociception, memory, anxiety, and other biological functions. Nocistatin acts as a functional antagonist to N/OFQ in several functions, but their neuro-anatomical sites of interaction are unknown. We investigated the effect of combined intracerebroventricular (i.c.v.) injection of nocistatin with N/OFQ, on N/OFQ induced c-Fos expression in the mouse hippocampus, using c-Fos immunohistochemistry. We found that co-injection of nocistatin with N/OFQ significantly attenuated N/OFQ induced c-Fos expression in the hippocampus. © 2007 Elsevier Ltd. All rights reserved.
Source Title: Neuropeptides
ISSN: 01434179
DOI: 10.1016/j.npep.2007.04.002
Appears in Collections:Staff Publications

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