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Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.vaccine.2006.03.040
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dc.titleA short report on highlights of worldwide development of RIX4414: A Singaporean experience
dc.contributor.authorPhua, K.B.
dc.contributor.authorQuak, S.H.
dc.contributor.authorEmmanuel, S.
dc.contributor.authorGoh, P.S.C.
dc.contributor.authorHan, H.H.
dc.contributor.authorBock, H.L.
dc.contributor.authorHardt, K.
dc.contributor.authorDe, Vos B.
dc.date.accessioned2011-08-16T07:42:49Z
dc.date.available2011-08-16T07:42:49Z
dc.date.issued2006
dc.identifier.citationPhua, K.B., Quak, S.H., Emmanuel, S., Goh, P.S.C., Han, H.H., Bock, H.L., Hardt, K., De, Vos B. (2006). A short report on highlights of worldwide development of RIX4414: A Singaporean experience. Vaccine 24 (18) : 3782-3783. ScholarBank@NUS Repository. https://doi.org/10.1016/j.vaccine.2006.03.040
dc.identifier.issn0264410X
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/25663
dc.description.abstractIn Singapore, we conducted a phase II randomized, double-blind, placebo-controlled dose ranging study using an attenuated human rotavirus vaccine, RIX4414. Altogether, 2464 healthy infants were recruited. Two oral doses of vaccine at 104.7, 105.2 or 106.1 ffu or placebo were administered with routine immunizations at 3 and 4 months of age. Seroconversion and 'vaccine take' in the vaccine groups 1-month post dose 2 varied from 76 to 91% and 98 to 100% respectively. Vaccine was well tolerated and did not interfere with response of concomitantly administered vaccines. © 2006 Elsevier Ltd. All rights reserved.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.vaccine.2006.03.040
dc.sourceScopus
dc.subjectAttenuated human rotavirus vaccine
dc.subjectPhase II clinical trial
dc.typeArticle
dc.contributor.departmentPAEDIATRICS
dc.description.doi10.1016/j.vaccine.2006.03.040
dc.description.sourcetitleVaccine
dc.description.volume24
dc.description.issue18
dc.description.page3782-3783
dc.identifier.isiut000237944100013
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