Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.ijrobp.2005.06.027
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dc.titleCorrelation between MR imaging-derived nasopharyngeal carcinoma tumor volume and TNM system
dc.contributor.authorChong, V.F.H.
dc.contributor.authorZhou, J.-Y.
dc.contributor.authorChan, K.-L.
dc.contributor.authorKhoo, J.B.K.
dc.contributor.authorHuang, J.
dc.date.accessioned2011-08-16T05:14:21Z
dc.date.available2011-08-16T05:14:21Z
dc.date.issued2006
dc.identifier.citationChong, V.F.H., Zhou, J.-Y., Chan, K.-L., Khoo, J.B.K., Huang, J. (2006). Correlation between MR imaging-derived nasopharyngeal carcinoma tumor volume and TNM system. International Journal of Radiation Oncology Biology Physics 64 (1) : 72-76. ScholarBank@NUS Repository. https://doi.org/10.1016/j.ijrobp.2005.06.027
dc.identifier.issn03603016
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/25505
dc.description.abstractPurpose: To measure nasopharyngeal carcinoma tumor volume based on magnetic resonance images using a validated semiautomated measurement methodology and correlate tumor volume with TNM T classification. Methods and Materials: The study population consisted of 206 consecutive nasopharyngeal carcinoma patients who had magnetic resonance imaging staging scans. Tumor volume was measured using a semisupervised knowledge-based fuzzy clustering algorithm. Patients were divided into 4 groups according to TNM T classification. The difference in tumor volumes among the various TNM T-classification groups was examined. Results: The mean tumor volume in each T-classification group is as follows: T1, 8.6 mL ± 5.0 (standard deviation [SD]); T2, 18.1 mL ± 8.1 (SD); T3, 25.8 mL ± 14.1 (SD); and T4, 36.2 mL ± 18.9 (SD). The mean tumor volume increased significantly with advancing T classification (p < 0.0001). Tumor volume in a more advanced T group was significantly larger than that in an adjacent early T group (p < 0.01). Conclusion: Validated magnetic resonance imaging-based tumor volume shows positive correlation between tumor volume and advancing T-classification groups. It may be possible to incorporate tumor volume as an additional prognostic factor into the existing TNM system. © 2006 Elsevier Inc.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.ijrobp.2005.06.027
dc.sourceScopus
dc.subjectMagnetic resonance tumor volume measurement
dc.subjectNasopharyngeal carcinoma
dc.subjectTNM stage
dc.typeConference Paper
dc.contributor.departmentDIAGNOSTIC RADIOLOGY
dc.description.doi10.1016/j.ijrobp.2005.06.027
dc.description.sourcetitleInternational Journal of Radiation Oncology Biology Physics
dc.description.volume64
dc.description.issue1
dc.description.page72-76
dc.description.codenIOBPD
dc.identifier.isiut000234442200011
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