Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.ijcard.2008.03.098
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dc.titleDown regulation of immuno-detectable cardiac connexin-43 in BALB/c mice following acute fasting
dc.contributor.authorMcLachlan, C.S.
dc.contributor.authorAlmsherqi, Z.A.
dc.contributor.authorLeong, S.T.
dc.contributor.authorDeng, Y.
dc.contributor.authorMossop, P.
dc.contributor.authorSuzuki, J.
dc.date.accessioned2011-07-27T06:39:08Z
dc.date.available2011-07-27T06:39:08Z
dc.date.issued2009
dc.identifier.citationMcLachlan, C.S., Almsherqi, Z.A., Leong, S.T., Deng, Y., Mossop, P., Suzuki, J. (2009). Down regulation of immuno-detectable cardiac connexin-43 in BALB/c mice following acute fasting. International Journal of Cardiology 136 (1) : 99-102. ScholarBank@NUS Repository. https://doi.org/10.1016/j.ijcard.2008.03.098
dc.identifier.issn01675273
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/24969
dc.description.abstractAcute starvation effects for connexin-43 protein expression, in the heart, had not been previously explored. Hence we examined acute fasting on the myocardial immuno-histochemical expression of connexin-43 in 3 groups of 8-week old female BALB/c mice. Groups consisted of control mice (n = 5), fasting for 24 h (N = 5) and 48 h (N = 3). Under light microscopy all control fed cases revealed the presence of some immuno-detectable staining for connexin-43 that is either present or weakly observed in some or all of the regions of interest, that include the cross-sectional left ventricular sub-endocardium, mid-myocardium and papillary muscle. Whereas mice that underwent 24 or 48 h of acute starvation, connexin-43 expression was either difficult to detect visually (N = 3) or was completely absent (N = 5) at 40× magnification using a light microscope. In starved mice with no membrane staining for connexin-43 we observed an increase in the intracellular accumulation of cytoplasmic connexin-43 expression. © 2008 Elsevier Ireland Ltd. All rights reserved.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.ijcard.2008.03.098
dc.sourceScopus
dc.subjectAcute starvation
dc.subjectCardiac myocyte
dc.subjectConnexin-43
dc.subjectMyocardium
dc.typeArticle
dc.contributor.departmentPHYSIOLOGY
dc.description.doi10.1016/j.ijcard.2008.03.098
dc.description.sourcetitleInternational Journal of Cardiology
dc.description.volume136
dc.description.issue1
dc.description.page99-102
dc.identifier.isiut000267872400019
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