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Title: Prevalence and Risk Factors of Retinal Arteriolar Emboli: The Singapore Malay Eye Study
Authors: Cheung, N.
Lim, L.
Wang, J.J.
Islam, F.M.A.
Wong, T.Y.
Wang, J.J.
Mitchell, P.
Saw, S.M. 
Aung, T. 
Issue Date: 2008
Citation: Cheung, N., Lim, L., Wang, J.J., Islam, F.M.A., Wong, T.Y., Wang, J.J., Mitchell, P., Saw, S.M., Aung, T. (2008). Prevalence and Risk Factors of Retinal Arteriolar Emboli: The Singapore Malay Eye Study. American Journal of Ophthalmology 146 (4) : 620-624. ScholarBank@NUS Repository.
Abstract: Purpose: To examine the prevalence and risk factors of retinal arteriolar emboli, a risk predictor of stroke, in an Asian population. Design: Population-based cross-sectional study. Methods: Retinal emboli were ascertained from retinal photographs obtained from both eyes of 3,265 Asian Malays, aged 40 to 80 years, according to a standardized protocol. Risk factors were assessed from detailed standardized interviews, clinical examinations, and laboratory investigations. Results: The overall prevalence of retinal emboli was 0.6% (95% confidence interval [CI], 0.58 to 0.62). A finding of retinal emboli was strongly associated with increasing age (P = .005, for trend), but age-stratified prevalence rates were still lower than those reported from previous population-based studies of White persons. After adjusting for age and gender, the presence of retinal emboli was associated with cigarette smoking (odds ratio [OR], 5.96; 95% CI, 1.75 to 20.32), elevated total cholesterol (OR, 5.21; 95% CI, 1.93 to 12.82), low-density lipoprotein cholesterol (OR, 2.98; 95% CI, 1.20 to 7.39), and self-reported history of angina (OR, 5.67; 95% CI, 1.62 to 19.91). These associations remained significant in multivariate analysis with additional adjustment for other risk factors. Conclusions: Retinal emboli are less common in Asians than in similarly aged White persons, but are associated with similar cardiovascular risk factors. © 2008 Elsevier Inc. All rights reserved.
Source Title: American Journal of Ophthalmology
ISSN: 00029394
Appears in Collections:Staff Publications

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