Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.chroma.2008.01.011
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dc.titleEvaluation of the extraction efficiency of thermally labile bioactive compounds in Gastrodia elata Blume by pressurized hot water extraction and microwave-assisted extraction
dc.contributor.authorTeo, C.C.
dc.contributor.authorTan, S.N.
dc.contributor.authorYong, J.W.H.
dc.contributor.authorHew, C.S.
dc.contributor.authorOng, E.S.
dc.date.accessioned2011-07-25T06:58:46Z
dc.date.available2011-07-25T06:58:46Z
dc.date.issued2008
dc.identifier.citationTeo, C.C., Tan, S.N., Yong, J.W.H., Hew, C.S., Ong, E.S. (2008). Evaluation of the extraction efficiency of thermally labile bioactive compounds in Gastrodia elata Blume by pressurized hot water extraction and microwave-assisted extraction. Journal of Chromatography A 1182 (1) : 34-40. ScholarBank@NUS Repository. https://doi.org/10.1016/j.chroma.2008.01.011
dc.identifier.issn00219673
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/24450
dc.description.abstractOur earlier work showed that the stability of the bioactive compounds gastrodin (GA) and vanillyl alcohol (VA) in Gastrodia elata Blume behaved differently with varying compositions of water-ethanol using pressurized liquid extraction (PLE) at room temperature. To have a better understanding of the extraction process of these thermally labile compounds under elevated temperature conditions, pressurized hot water extraction (PHWE) and microwave-assisted extraction (MAE) methods were proposed. PHWE and MAE showed that GA and VA could be extracted using pure water under optimized conditions of temperature and extraction time. The extraction efficiency of GA and VA by the proposed methods was found to be higher or comparable to heating under reflux using water. The marker compounds present in the plant extracts were determined by RP-HPLC. The optimized conditions were found to be different for the two proposed methods on extraction of GA and VA. The method precision (RSD, n = 6) was found to vary from 0.92% to 3.36% for the two proposed methods on different days. Hence, PHWE and MAE methods were shown to be feasible alternatives for the extraction of thermally labile marker compounds present in medicinal plants. © 2008 Elsevier B.V. All rights reserved.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.chroma.2008.01.011
dc.sourceScopus
dc.subjectGastrodia elata Blume
dc.subjectGastrodin
dc.subjectMicrowave-assisted extraction
dc.subjectPressurized hot water extraction
dc.subjectVanillyl alcohol
dc.typeArticle
dc.contributor.departmentCOMMUNITY,OCCUPATIONAL & FAMILY MEDICINE
dc.description.doi10.1016/j.chroma.2008.01.011
dc.description.sourcetitleJournal of Chromatography A
dc.description.volume1182
dc.description.issue1
dc.description.page34-40
dc.identifier.isiut000253869800003
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