Please use this identifier to cite or link to this item:
Title: Therapeutic potential of plants as anti-microbials for drug discovery
Authors: Perumal, Samy R. 
Gopalakrishnakone, P. 
Keywords: ethnopharmacology
human clinical trails
secondary metabolites
traditional medicine
Issue Date: 2010
Citation: Perumal, Samy R., Gopalakrishnakone, P. (2010). Therapeutic potential of plants as anti-microbials for drug discovery. Evidence-based Complementary and Alternative Medicine 7 (3) : 283-294. ScholarBank@NUS Repository.
Abstract: The uses of traditional medicinal plants for primary health care have steadily increased worldwide in recent years. Scientists are in search of new phytochemicals that could be developed as useful anti-microbials for treatment of infectious diseases. Currently, out of 80 of pharmaceuticals derived from plants, very few are now being used as anti-microbials. Plants are rich in a wide variety of secondary metabolites that have found anti-microbial properties. This review highlights the current status of traditional medicine, its contribution to modern medicine, recent trends in the evaluation of anti-microbials with a special emphasis upon some tribal medicine, in vitro and in vivo experimental design for screening, and therapeutic efficacy in safety and human clinical trails for commercial outlet. Many of these commercially available compounds are crude preparations administered without performing human clinical trials. Recent methods are useful to standardize the extraction for scientific investigation of new phytochemicals and anti-microbials of traditionally used plants. It is concluded that once the local ethnomedical preparations of traditional sources are scientifically evaluated before dispensing they should replace existing drugs commonly used for the therapeutic treatment of infection. This method should be put into practice for future investigations in the field of ethnopharmacology, phytochemistry, ethnobotany and other biological fields for drug discovery. © 2008 The Author(s).
Source Title: Evidence-based Complementary and Alternative Medicine
ISSN: 1741427X
DOI: 10.1093/ecam/nen036
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.


checked on May 26, 2023


checked on May 26, 2023

Page view(s)

checked on May 25, 2023

Google ScholarTM



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.