Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/235779
Title: ASYMMETRIC PHOSPHINE CATALYSIS: METHODOLOGY AND APPLICATIONS IN THE CONSTRUCTION OF CHIRAL STEREOGENIC CENTERS AND AXES
Authors: TAN CHUAN XIANG, ALVIN
Keywords: Organic Chemistry, Methodology, Chirality, Asymmetric, Phosphine Catalysis, Atropisomer
Issue Date: 3-Aug-2022
Citation: TAN CHUAN XIANG, ALVIN (2022-08-03). ASYMMETRIC PHOSPHINE CATALYSIS: METHODOLOGY AND APPLICATIONS IN THE CONSTRUCTION OF CHIRAL STEREOGENIC CENTERS AND AXES. ScholarBank@NUS Repository.
Abstract: As phosphine catalysis continues to progress, new methodologies involving novel substrates to create both useful and interesting molecular architectures are considered of great importance today. Over the past few decades, asymmetric phosphine catalysis has evolved to be well-known as a powerful toolkit for different organic transformations, including the development of chiral stereogenic centers and more recently chiral axes. This thesis will present some of the newly developed strategies bestowed upon by our group’s amino acid-derived phosphine catalysts in the construction of chiral centers and axes, and their corresponding applications towards the synthesis of natural products and pharmaceutical drugs.
URI: https://scholarbank.nus.edu.sg/handle/10635/235779
Appears in Collections:Ph.D Theses (Open)

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