Please use this identifier to cite or link to this item: https://doi.org/10.1097/HJH.0000000000002617
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dc.titleOrthostatic blood pressure recovery associates with physical performance, frailty and number of falls in geriatric outpatients
dc.contributor.authorMol, Arjen
dc.contributor.authorSlangen, Lois RN
dc.contributor.authorvan Wezel, Richard JA
dc.contributor.authorMaier, Andrea B
dc.contributor.authorMeskers, Carel GM
dc.date.accessioned2022-11-29T03:16:26Z
dc.date.available2022-11-29T03:16:26Z
dc.date.issued2021-01-01
dc.identifier.citationMol, Arjen, Slangen, Lois RN, van Wezel, Richard JA, Maier, Andrea B, Meskers, Carel GM (2021-01-01). Orthostatic blood pressure recovery associates with physical performance, frailty and number of falls in geriatric outpatients. JOURNAL OF HYPERTENSION 39 (1) : 101-106. ScholarBank@NUS Repository. https://doi.org/10.1097/HJH.0000000000002617
dc.identifier.issn0263-6352
dc.identifier.issn1473-5598
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/234890
dc.description.abstractObjective: Blood pressure (BP) recovery after orthostatic hypotension might be important to prevent cerebral hypoperfusion episodes in older adults, and be related to better clinical outcome. The objective was to study the relationship between BP recovery and clinical outcome, that is physical and cognitive performance, frailty and falls, in geriatric outpatients. Methods: One hundred and sixty-eight geriatric outpatients underwent continuous (beat-to-beat) BP measurements during standing up, and a comprehensive geriatric assessment, including assessment of physical performance (chair stand test), cognitive performance (Mini Mental State Examination), frailty (Fried criteria) and falls in the previous year. BP recovery was evaluated at 15-30, 30-60, 60-120 and 120-180 s after standing up and defined as mean SBP and DBP in the respective time intervals minus baseline BP. Associations with clinical outcome were assessed using linear (physical and cognitive performance and frailty) and logistic (falls) regression, adjusting for age, sex, baseline BP and initial BP drop. Results: SBP recovery was associated with frailty (30-60 s interval; b=0.013, P=0.02) and falls (30-60 s interval; odds ratio=1.024, P=0.02). DBP recovery was associated with physical performance (30-60 s interval; b=0.215, P=0.01), frailty (30-60 s interval; b=0.028, P=0.02) and falls (30- 60 s interval; odds ratio=1.039, P=0.04). Neither SBP nor DBP recovery was associated with cognitive performance. Conclusion: DBP recovery was particularly associated with clinical outcome in geriatric outpatients, suggesting BP recovery to be of clinical interest.
dc.language.isoen
dc.publisherLIPPINCOTT WILLIAMS & WILKINS
dc.sourceElements
dc.subjectScience & Technology
dc.subjectLife Sciences & Biomedicine
dc.subjectPeripheral Vascular Disease
dc.subjectCardiovascular System & Cardiology
dc.subjectblood pressure determination
dc.subjectcardiovascular system
dc.subjectcognition
dc.subjectfalls
dc.subjectfrailty
dc.subjecthypotension
dc.subjectorthostatic hypotension
dc.subjectphysical functional performance
dc.typeArticle
dc.date.updated2022-11-29T01:37:34Z
dc.contributor.departmentDEPT OF MEDICINE
dc.description.doi10.1097/HJH.0000000000002617
dc.description.sourcetitleJOURNAL OF HYPERTENSION
dc.description.volume39
dc.description.issue1
dc.description.page101-106
dc.published.statePublished
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