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Title: Prevalence of IgE-mediated cow milk, egg, and peanut allergy in young Singapore children.
Authors: Lee, Alison Joanne
Tham, Elizabeth Huiwen 
Goh, Anne Eng-Neo 
Tang, Wern-Ee 
Tung, Yew-Cheong
Yeo, Yehudi 
Tsou, Keith 
Lee, Le-Ye 
Soh, Jian-Yi 
Labastida, Cesar Brence
Wang, Ping-Ping
Tan, Michelle Mei-Ling
Cheng, Hsin Yue
Chan, Yiong-Huak 
Van Bever, Hugo 
Shek, Lynette Pei-Chi 
Lee, Bee-Wah 
Keywords: Asia
Cow’s milk
Food allergy
Issue Date: Jul-2022
Publisher: Asia Pacific Association of Allergy, Asthma, and Clinical Immunology
Citation: Lee, Alison Joanne, Tham, Elizabeth Huiwen, Goh, Anne Eng-Neo, Tang, Wern-Ee, Tung, Yew-Cheong, Yeo, Yehudi, Tsou, Keith, Lee, Le-Ye, Soh, Jian-Yi, Labastida, Cesar Brence, Wang, Ping-Ping, Tan, Michelle Mei-Ling, Cheng, Hsin Yue, Chan, Yiong-Huak, Van Bever, Hugo, Shek, Lynette Pei-Chi, Lee, Bee-Wah (2022-07). Prevalence of IgE-mediated cow milk, egg, and peanut allergy in young Singapore children.. Asia Pac Allergy 12 (3) : e31-. ScholarBank@NUS Repository.
Abstract: BACKGROUND: The rising prevalence of food allergy reported in the United States, UK, and Australia may be attributable to the rise in peanut allergy prevalence. The food allergy prevalence in other parts of the world such as Asia is, however, less well documented. OBJECTIVE: This study aimed to evaluate the prevalence of cow's milk, egg, and peanut allergies in a general population of Singaporean children below 30 months of age. METHODS: A total of 4,115 children from the general population who attended well-baby visits between 2011 and 2015 completed standardized questionnaires to elicit a convincing history of food allergy to estimate the population prevalence of food allergies. RESULTS: The prevalence of a convincing history of cow's milk allergy was 0.51% (95% confidence interval [CI], 0.3-0.7), hen's egg allergy 1.43% (95% CI, 1.1-1.8), and peanut allergy 0.27% (95% CI, 0.12-0.42). Of the 15 of 59 children with a convincing history of hen's egg allergy who consented, 12 (80%) had corroborative positive skin prick tests. CONCLUSION: The prevalence of food allergy, in particular peanut allergy, in children below 2 years of age is lower in this South East Asian population than reported in Western cohorts. Further research should focus on deciphering differential risk factors for food allergy across different geographical locations.
Source Title: Asia Pac Allergy
ISSN: 2233-8276
DOI: 10.5415/apallergy.2022.12.e31
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