Please use this identifier to cite or link to this item: https://doi.org/10.3389/fcvm.2022.812680
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dc.titleThe Associations Between Preoperative Anthropometry and Postoperative Outcomes in Infants Undergoing Congenital Heart Surgery
dc.contributor.authorLim, Jia Yi Joel
dc.contributor.authorWee, Rui Wen Bryan
dc.contributor.authorGandhi, Mihir
dc.contributor.authorLim, Yee Phong
dc.contributor.authorTan, Li Nien Michelle
dc.contributor.authorQuek, Swee Chye
dc.contributor.authorAw, Marion M
dc.contributor.authorChen, Ching Kit
dc.date.accessioned2022-11-22T00:38:28Z
dc.date.available2022-11-22T00:38:28Z
dc.date.issued2022-04-01
dc.identifier.citationLim, Jia Yi Joel, Wee, Rui Wen Bryan, Gandhi, Mihir, Lim, Yee Phong, Tan, Li Nien Michelle, Quek, Swee Chye, Aw, Marion M, Chen, Ching Kit (2022-04-01). The Associations Between Preoperative Anthropometry and Postoperative Outcomes in Infants Undergoing Congenital Heart Surgery. FRONTIERS IN CARDIOVASCULAR MEDICINE 9. ScholarBank@NUS Repository. https://doi.org/10.3389/fcvm.2022.812680
dc.identifier.issn2297-055X
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/234737
dc.description.abstractAim: We explored the association between preoperative anthropometry and biochemistry, and postoperative outcomes in infants with CHD after cardiac surgery, as infants with congenital heart disease (CHD) often have feeding difficulties and malnutrition. Methodology: This was a retrospective review of infants (≤ 1-year-old) who underwent congenital heart surgery. Preoperative anthropometryin terms of preoperative weight-for-age z-score (WAZ), length-for-age z-score (LAZ), as well as preoperative serum albumin and hemoglobin concentrations, were evaluated against 6-month mortality, and morbidity outcomes including postoperative complications, vasoactive inotrope score, duration of mechanical ventilation, length of stay in the pediatric intensive care unit and in hospital, using the logistic regression or median regression models accounting for infant-level clustering. Results: One hundred and ninety-nine operations were performed in 167 infants. Mean gestational age at birth was 38.0 (SD 2.2) weeks (range 26 to 41 weeks). Thirty (18.0%) infants were born preterm (<37 weeks). The commonest acyanotic and cyanotic lesions were ventricular septal defect (26.3%, 44/167), and tetralogy of Fallot (13.8%, 23/167), respectively. Mean age at cardiac surgery was 94 (SD 95) days. Feeding difficulties, including increased work of breathing during feeding, diaphoresis, choking or coughing during feeding, and inability to complete feeds, was present in 54.3% (108/199) of infants prior to surgery, of which 21.6% (43/199) required tube feeding. The mean preoperative WAZ was−1.31 (SD 1.79). Logistic regression models showed that low preoperative WAZ was associated with increased risk of postoperative complications (odds ratio 1.82; p = 0.02), and 6-month mortality (odds ratio 2.38; p = 0.008) following CHD surgery. There was no meaningful association between the other preoperative variables and other outcomes. Conclusion: More than 50% of infants with CHD undergoing cardiac surgery within the first year of life have feeding difficulties, of which 22% require to be tube-fed. Low preoperative WAZ is associated with increased postoperative complications and 6-month mortality.
dc.language.isoen
dc.publisherFRONTIERS MEDIA SA
dc.sourceElements
dc.subjectScience & Technology
dc.subjectLife Sciences & Biomedicine
dc.subjectCardiac & Cardiovascular Systems
dc.subjectCardiovascular System & Cardiology
dc.subjectcongenital heart disease
dc.subjectfeeding difficulties
dc.subjectinfants
dc.subjectcardiac surgery
dc.subjectnutritional status
dc.subjectpreoperative weight-for age z-score
dc.subjectpostoperative complications
dc.subject6-month mortality
dc.subjectNUTRITIONAL-STATUS
dc.subjectCHILDREN
dc.subjectMALNUTRITION
dc.subjectDISEASE
dc.subjectGROWTH
dc.subjectOPERATION
dc.subjectMORTALITY
dc.typeArticle
dc.date.updated2022-11-20T05:39:31Z
dc.contributor.departmentDEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
dc.contributor.departmentDEPT OF PAEDIATRICS
dc.contributor.departmentDEPT OF MEDICINE
dc.description.doi10.3389/fcvm.2022.812680
dc.description.sourcetitleFRONTIERS IN CARDIOVASCULAR MEDICINE
dc.description.volume9
dc.published.statePublished
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