Please use this identifier to cite or link to this item: https://doi.org/10.3390/nu14112190
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dc.titleMixed Milk Feeding: A New Approach to Describe Feeding Patterns in the First Year of Life Based on Individual Participant Data from Two Randomised Controlled Trials
dc.contributor.authorPapadopoulos, Nikolaos G
dc.contributor.authorBalan, Theodor A
dc.contributor.authorvan der Merwe, Liandre F
dc.contributor.authorPang, Wei Wei
dc.contributor.authorMichaelis, Louise J
dc.contributor.authorShek, Lynette P
dc.contributor.authorVandenplas, Yvan
dc.contributor.authorTeoh, Oon Hoe
dc.contributor.authorFiocchi, Alessandro G
dc.contributor.authorChong, Yap Seng
dc.date.accessioned2022-11-18T05:12:43Z
dc.date.available2022-11-18T05:12:43Z
dc.date.issued2022-06-01
dc.identifier.citationPapadopoulos, Nikolaos G, Balan, Theodor A, van der Merwe, Liandre F, Pang, Wei Wei, Michaelis, Louise J, Shek, Lynette P, Vandenplas, Yvan, Teoh, Oon Hoe, Fiocchi, Alessandro G, Chong, Yap Seng (2022-06-01). Mixed Milk Feeding: A New Approach to Describe Feeding Patterns in the First Year of Life Based on Individual Participant Data from Two Randomised Controlled Trials. NUTRIENTS 14 (11). ScholarBank@NUS Repository. https://doi.org/10.3390/nu14112190
dc.identifier.issn20726643
dc.identifier.issn20726643
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/234704
dc.description.abstract‘Mixed Milk Feeding’ (MMF), whereby infants are fed with both breastmilk and infant formula during the same period, is a common feeding practice. Despite its high prevalence, knowledge regarding MMF practices and their association with (health) outcomes is limited, potentially because MMF behaviours are highly variable and difficult to standardise longitudinally. In this paper, we applied a statistical clustering algorithm on individual infant feeding data collected over the first year of life from two clinical trials: ‘TEMPO’ (n = 855) and ‘Venus’ (n = 539); these studies were conducted in different years and world regions. In TEMPO, more than half of infants were MMF. Four distinct MMF clusters were identified: early exclusive formula feeding (32%), later exclusive formula feeding (25%), long-term MMF (21%), and mostly breastfeeding (22%). The same method applied to ‘Venus’ resulted in comparable clusters, building trust in the robustness of the cluster approach. These results demonstrate that distinct MMF patterns can be identified, which may be applicable to diverse populations. These insights could support the design of future research studying the impact of infant feeding patterns on health outcomes. To standardise this in future research, it is important to establish a unified definition of MMF.
dc.language.isoen
dc.publisherMDPI
dc.sourceElements
dc.subjectScience & Technology
dc.subjectLife Sciences & Biomedicine
dc.subjectNutrition & Dietetics
dc.subjectbreastfeeding
dc.subjectformula feeding
dc.subjectinfant
dc.subjectk-means clustering
dc.subjectmixed milk feeding
dc.subjectBREAST-MILK
dc.subjectDURATION
dc.subjectFORMULA
dc.subjectINFANT
dc.subjectRISK
dc.subjectASSOCIATION
dc.subjectTRENDS
dc.subjectKML3D
dc.typeArticle
dc.date.updated2022-11-18T03:46:51Z
dc.contributor.departmentDEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
dc.contributor.departmentDEAN'S OFFICE (MEDICINE)
dc.description.doi10.3390/nu14112190
dc.description.sourcetitleNUTRIENTS
dc.description.volume14
dc.description.issue11
dc.published.statePublished
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