Please use this identifier to cite or link to this item: https://doi.org/10.3389/fped.2021.833205
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dc.titlePCRRT Expert Committee ICONIC Position Paper on Prescribing Kidney Replacement Therapy in Critically Sick Children With Acute Liver Failure
dc.contributor.authorRaina, R
dc.contributor.authorSethi, SK
dc.contributor.authorFiller, G
dc.contributor.authorMenon, S
dc.contributor.authorMittal, A
dc.contributor.authorKhooblall, A
dc.contributor.authorKhooblall, P
dc.contributor.authorChakraborty, R
dc.contributor.authorAdnani, H
dc.contributor.authorVijayvargiya, N
dc.contributor.authorTeo, S
dc.contributor.authorBhatt, G
dc.contributor.authorKoh, LJ
dc.contributor.authorMourani, C
dc.contributor.authorde Sousa Tavares, M
dc.contributor.authorAlhasan, K
dc.contributor.authorForbes, M
dc.contributor.authorDhaliwal, M
dc.contributor.authorRaghunathan, V
dc.contributor.authorBroering, D
dc.contributor.authorSultana, A
dc.contributor.authorMontini, G
dc.contributor.authorBrophy, P
dc.contributor.authorMcCulloch, M
dc.contributor.authorBunchman, T
dc.contributor.authorYap, HK
dc.contributor.authorTopalglu, R
dc.contributor.authorDíaz-González de Ferris, M
dc.date.accessioned2022-11-17T06:46:34Z
dc.date.available2022-11-17T06:46:34Z
dc.date.issued2022-02-02
dc.identifier.citationRaina, R, Sethi, SK, Filler, G, Menon, S, Mittal, A, Khooblall, A, Khooblall, P, Chakraborty, R, Adnani, H, Vijayvargiya, N, Teo, S, Bhatt, G, Koh, LJ, Mourani, C, de Sousa Tavares, M, Alhasan, K, Forbes, M, Dhaliwal, M, Raghunathan, V, Broering, D, Sultana, A, Montini, G, Brophy, P, McCulloch, M, Bunchman, T, Yap, HK, Topalglu, R, Díaz-González de Ferris, M (2022-02-02). PCRRT Expert Committee ICONIC Position Paper on Prescribing Kidney Replacement Therapy in Critically Sick Children With Acute Liver Failure. Frontiers in Pediatrics 9 : 833205-. ScholarBank@NUS Repository. https://doi.org/10.3389/fped.2021.833205
dc.identifier.issn2296-2360
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/234663
dc.description.abstractManagement of acute liver failure (ALF) and acute on chronic liver failure (ACLF) in the pediatric population can be challenging. Kidney manifestations of liver failure, such as hepatorenal syndrome (HRS) and acute kidney injury (AKI), are increasingly prevalent and may portend a poor prognosis. The overall incidence of AKI in children with ALF has not been well-established, partially due to the difficulty of precisely estimating kidney function in these patients. The true incidence of AKI in pediatric patients may still be underestimated due to decreased creatinine production in patients with advanced liver dysfunction and those with critical conditions including shock and cardiovascular compromise with poor kidney perfusion. Current treatment for kidney dysfunction secondary to liver failure include conservative management, intravenous fluids, and kidney replacement therapy (KRT). Despite the paucity of evidence-based recommendations concerning the application of KRT in children with kidney dysfunction in the setting of ALF, expert clinical opinions have been evaluated regarding the optimal modalities and timing of KRT, dialysis/replacement solutions, blood and dialysate flow rates and dialysis dose, and anticoagulation methods.
dc.publisherFrontiers Media SA
dc.sourceElements
dc.subjectALF
dc.subjectPALF
dc.subjectacute kidney injury (AKI)
dc.subjectacute liver failure (ALF)
dc.subjectpediatric
dc.typeArticle
dc.date.updated2022-11-17T03:43:15Z
dc.contributor.departmentDEPT OF PAEDIATRICS
dc.description.doi10.3389/fped.2021.833205
dc.description.sourcetitleFrontiers in Pediatrics
dc.description.volume9
dc.description.page833205-
dc.published.statePublished
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