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Title: Bioactive agent-loaded electrospun nanofiber membranes for accelerating healing process: A review
Authors: Mousavi, Seyyed-Mojtaba
Nejad, Zohre Mousavi
Hashemi, Seyyed Alireza
Salari, Marjan
Gholami, Ahmad
Ramakrishna, Seeram 
Chiang, Wei-Hung
Lai, Chin Wei
Keywords: Bioactive molecules
Tissue engineering
Wound dressing
Wound healing
Issue Date: 13-Sep-2021
Publisher: MDPI
Citation: Mousavi, Seyyed-Mojtaba, Nejad, Zohre Mousavi, Hashemi, Seyyed Alireza, Salari, Marjan, Gholami, Ahmad, Ramakrishna, Seeram, Chiang, Wei-Hung, Lai, Chin Wei (2021-09-13). Bioactive agent-loaded electrospun nanofiber membranes for accelerating healing process: A review. Membranes 11 (9) : 702. ScholarBank@NUS Repository.
Rights: Attribution 4.0 International
Abstract: Despite the advances that have been achieved in developing wound dressings to date, wound healing still remains a challenge in the healthcare system. None of the wound dressings currently used clinically can mimic all the properties of normal and healthy skin. Electrospinning has gained remarkable attention in wound healing applications because of its excellent ability to form nanostructures similar to natural extracellular matrix (ECM). Electrospun dressing accelerates the wound healing process by transferring drugs or active agents to the wound site sooner. This review provides a concise overview of the recent developments in bioactive electrospun dressings, which are effective in treating acute and chronic wounds and can successfully heal the wound. We also discuss bioactive agents used to incorporate electrospun wound dressings to improve their therapeutic potential in wound healing. In addition, here we present commercial dressings loaded with bioactive agents with a comparison between their features and capabilities. Furthermore, we discuss challenges and promises and offer suggestions for future research on bioactive agent-loaded nanofiber membranes to guide future researchers in designing more effective dressing for wound healing and skin regeneration. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
Source Title: Membranes
ISSN: 2077-0375
DOI: 10.3390/membranes11090702
Rights: Attribution 4.0 International
Appears in Collections:Staff Publications

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