Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.jlr.2021.100138
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dc.titleRecommendations for good practice in ms-based lipidomics
dc.contributor.authorKöfeler, H.C.
dc.contributor.authorAhrends, Robert
dc.contributor.authorBaker, Erin S.
dc.contributor.authorEkroos, Kim
dc.contributor.authorHan, Xianlin
dc.contributor.authorHoffmann, Nils
dc.contributor.authorHolcapek, Michal
dc.contributor.authorWenk, Markus R.
dc.contributor.authorLiebisch, Gerhard
dc.date.accessioned2022-10-11T08:04:03Z
dc.date.available2022-10-11T08:04:03Z
dc.date.issued2021-01-01
dc.identifier.citationKöfeler, H.C., Ahrends, Robert, Baker, Erin S., Ekroos, Kim, Han, Xianlin, Hoffmann, Nils, Holcapek, Michal, Wenk, Markus R., Liebisch, Gerhard (2021-01-01). Recommendations for good practice in ms-based lipidomics. Journal of Lipid Research 62 : 100138. ScholarBank@NUS Repository. https://doi.org/10.1016/j.jlr.2021.100138
dc.identifier.issn0022-2275
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/232150
dc.description.abstractIn the last 2 decades, lipidomics has become one of the fastest expanding scientific disciplines in biomedical research. With an increasing number of new research groups to the field, it is even more important to design guidelines for assuring high standards of data quality. The Lipidomics Standards Initiative is a community-based endeavor for the coordination of development of these best practice guidelines in lipidomics and is embedded within the International Lipidomics Society. It is the intention of this review to highlight the most quality-relevant aspects of the lipidomics workflow, including preanalytics, sample preparation, MS, and lipid species identification and quantitation. Furthermore, this review just does not only highlights examples of best practice but also sheds light on strengths, drawbacks, and pitfalls in the lipidomic analysis workflow. While this review is neither designed to be a step-by-step protocol by itself nor dedicated to a specific application of lipidomics, it should nevertheless provide the interested reader with links and original publications to obtain a comprehensive overview concerning the state-of-the-art practices in the field. © 2021 American Society for Biochemistry and Molecular Biology Inc.. All rights reserved.
dc.publisherAmerican Society for Biochemistry and Molecular Biology Inc.
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourceScopus OA2021
dc.subjectChromatography
dc.subjectIon mobility spectrometry
dc.subjectLC-MS
dc.subjectLipid identification
dc.subjectLipidomics
dc.subjectMetabolomics
dc.subjectMS
dc.subjectPhospholipids
dc.subjectSphingolipids
dc.typeReview
dc.contributor.departmentBIOCHEMISTRY
dc.description.doi10.1016/j.jlr.2021.100138
dc.description.sourcetitleJournal of Lipid Research
dc.description.volume62
dc.description.page100138
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