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Title: COVID-19 vaccination intention and vaccine characteristics influencing vaccination acceptance: a global survey of 17 countries
Authors: Wong, Li Ping
Alias, Haridah
Danaee, Mahmoud
Ahmed, Jamil
Lachyan, Abhishek
Cai, Carla Zi
Lin, Yulan
Hu, Zhijian
Tan, Si Ying 
Lu, Yixiao
Cai, Guoxi
Di Khanh Nguyen
Seheli, Farhana Nishat
Alhammadi, Fatma
Madhale, Milkar D.
Atapattu, Muditha
Quazi-Bodhanya, Tasmi
Mohajer, Samira
Zimet, Gregory D.
Zhao, Qinjian
Keywords: COVID-19 vaccine
Vaccination acceptance
Vaccination intention
Vaccine characteristics
Vaccine choice
Issue Date: 7-Oct-2021
Publisher: BioMed Central Ltd
Citation: Wong, Li Ping, Alias, Haridah, Danaee, Mahmoud, Ahmed, Jamil, Lachyan, Abhishek, Cai, Carla Zi, Lin, Yulan, Hu, Zhijian, Tan, Si Ying, Lu, Yixiao, Cai, Guoxi, Di Khanh Nguyen, Seheli, Farhana Nishat, Alhammadi, Fatma, Madhale, Milkar D., Atapattu, Muditha, Quazi-Bodhanya, Tasmi, Mohajer, Samira, Zimet, Gregory D., Zhao, Qinjian (2021-10-07). COVID-19 vaccination intention and vaccine characteristics influencing vaccination acceptance: a global survey of 17 countries. Infectious Diseases of Poverty 10 (1) : 122. ScholarBank@NUS Repository.
Rights: Attribution 4.0 International
Abstract: Background: The availability of various types of COVID-19 vaccines and diverse characteristics of the vaccines present a dilemma in vaccination choices, which may result in individuals refusing a particular COVID-19 vaccine offered, hence presenting a threat to immunisation coverage and reaching herd immunity. The study aimed to assess global COVID-19 vaccination intention, vaccine characteristics influencing vaccination acceptance and desirable vaccine characteristics influencing the choice of vaccines. Methods: An anonymous cross-sectional survey was conducted between 4 January and 5 March 2021 in 17 countries worldwide. Proportions and the corresponding 95% confidence intervals (CI) of COVID-19 vaccine acceptance and vaccine characteristics influencing vaccination acceptance were generated and compared across countries and regions. Multivariable logistic regression analysis was used to determine the factors associated with COVID-19 vaccine hesitancy. Results: Of the 19,714 responses received, 90.4% (95% CI 81.8–95.3) reported likely or extremely likely to receive COVID-19 vaccine. A high proportion of likely or extremely likely to receive the COVID-19 vaccine was reported in Australia (96.4%), China (95.3%) and Norway (95.3%), while a high proportion reported being unlikely or extremely unlikely to receive the vaccine in Japan (34.6%), the U.S. (29.4%) and Iran (27.9%). Males, those with a lower educational level and those of older age expressed a higher level of COVID-19 vaccine hesitancy. Less than two-thirds (59.7%; 95% CI 58.4–61.0) reported only being willing to accept a vaccine with an effectiveness of more than 90%, and 74.5% (95% CI 73.4–75.5) said they would accept a COVID-19 vaccine with minor adverse reactions. A total of 21.0% (95% CI 20.0–22.0) reported not accepting an mRNA vaccine and 51.8% (95% CI 50.3–53.1) reported that they would only accept a COVID-19 vaccine from a specific country-of-origin. Countries from the Southeast Asia region reported the highest proportion of not accepting mRNA technology. The highest proportion from Europe and the Americas would only accept a vaccine produced by certain countries. The foremost important vaccine characteristic influencing vaccine choice is adverse reactions (40.6%; 95% CI 39.3–41.9) of a vaccine and effectiveness threshold (35.1%; 95% CI 33.9–36.4). Conclusions: The inter-regional and individual country disparities in COVID-19 vaccine hesitancy highlight the importance of designing an efficient plan for the delivery of interventions dynamically tailored to the local population. Graphic Abstract: [Figure not available: see fulltext.]. © 2021, The Author(s).
Source Title: Infectious Diseases of Poverty
ISSN: 2095-5162
DOI: 10.1186/s40249-021-00900-w
Rights: Attribution 4.0 International
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