Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/229439
Title: Global Evolutionary Trend of the Prevalence of Primary Glomerulonephritis over the Past Three Decades
Authors: Woo, Keng-Thye
Chan, Choong-Meng
Chin, Yoke Mooi
Choong, Hui-Lin
Tan, Han-Kim
Foo, Marjorie
Anantharaman, Vathsala 
Lee, Grace SL
Chiang, Gilbert SC
Tan, Puay Hoon
Lim, Cheng Hong
Tan, Chorh Chuan 
Lee, Evan 
Tan, Hwee Boon
Fook-Chong, Stephanie
Lau, Yeow-Kok
Wong, Kok-Seng
Keywords: Science & Technology
Life Sciences & Biomedicine
Urology & Nephrology
Epidemiology, clinical
Focal segmental glomerulosclerosis
Glomerulonephritis
IgA nephritis
Renal biopsy
FOCAL SEGMENTAL GLOMERULOSCLEROSIS
PRIMARY GLOMERULAR-DISEASES
RENAL-DISEASES
CHANGING PATTERN
EPIDEMIOLOGY
BIOPSY
REGISTRY
ADULTS
FREQUENCY
HYPOTHESIS
Issue Date: 1-Jan-2010
Publisher: KARGER
Citation: Woo, Keng-Thye, Chan, Choong-Meng, Chin, Yoke Mooi, Choong, Hui-Lin, Tan, Han-Kim, Foo, Marjorie, Anantharaman, Vathsala, Lee, Grace SL, Chiang, Gilbert SC, Tan, Puay Hoon, Lim, Cheng Hong, Tan, Chorh Chuan, Lee, Evan, Tan, Hwee Boon, Fook-Chong, Stephanie, Lau, Yeow-Kok, Wong, Kok-Seng (2010-01-01). Global Evolutionary Trend of the Prevalence of Primary Glomerulonephritis over the Past Three Decades. NEPHRON CLINICAL PRACTICE 116 (4) : C337-C346. ScholarBank@NUS Repository.
Abstract: Objective: The prevalence of primary glomerulonephritis in Singapore is compared with that of 28 other countries to review changing trends in the evolution of primary glomerulonephritis in Asia and other countries. Method: 2,586 renal biopsies in Singapore over the past 3 decades were reviewed and compared with data from 28 other countries. Results: In the 1st decade most Asian countries have mesangial proliferative glomerulonephritis as the most common form of primary glomerulonephritis, and in the 3rd decade there has been a dramatic increase in focal and segmental glomerulosclerosis reflecting aging and obesity in keeping with more developed countries. IgA nephritis remains the commonest glomerulonephritis in many countries. Membranous glomerulonephritis continues to be more prevalent in Western countries while mesangial proliferative glomerulonephritis remains prevalent in many Asian countries. Conclusion: Apart from geographical and genetic influences, socioeconomic factors may play a role in the evolution of the biopsy pattern in some countries. Worldwide, the prevalence of focal segmental glomerulosclerosis continues to increase. In third world countries some of the commoner forms of glomerulonephritis are related to infections, in contrast to developed countries where the antigenic exposure may be related to diet, allergens and other industrial agents. Copyright © 2010 S. Karger AG, Basel.
Source Title: NEPHRON CLINICAL PRACTICE
URI: https://scholarbank.nus.edu.sg/handle/10635/229439
ISSN: 1660-2110
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