Please use this identifier to cite or link to this item: https://doi.org/10.1111/nep.12379
Title: Ethnic disparity in prevalence of diabetic kidney disease in an Asian primary healthcare cluster
Authors: Loh, Ping Tyug 
Toh, Matthias Paul Han Sim 
Molina, Joseph Antonio
Vathsala, Anantharaman 
Keywords: Science & Technology
Life Sciences & Biomedicine
Urology & Nephrology
Asian
diabetic kidney disease
ethnic disparity
prevalence
primary care
RISK-FACTORS
NEPHROPATHY
MICROALBUMINURIA
PROGRESSION
MANAGEMENT
CHINESE
COHORT
Issue Date: 1-Mar-2015
Publisher: WILEY
Citation: Loh, Ping Tyug, Toh, Matthias Paul Han Sim, Molina, Joseph Antonio, Vathsala, Anantharaman (2015-03-01). Ethnic disparity in prevalence of diabetic kidney disease in an Asian primary healthcare cluster. NEPHROLOGY 20 (3) : 216-223. ScholarBank@NUS Repository. https://doi.org/10.1111/nep.12379
Abstract: Aims Diabetic kidney disease (DKD) incidence is rising in Singapore. While measures to prevent onset and early detection of diabetes as well as optimal diabetes and blood pressure control are important, early detection and treatment of DKD at primary care are crucial to ameliorate its course. This study aimed to evaluate the prevalence of DKD in a primary care cluster in Singapore and identify its risk factors in a multi-ethnic Asian population. Methods A total of 57 594 patients with type 2 diabetes mellitus (T2DM) followed-up at the National Healthcare Group Polyclinics with estimated glomerular filtration rate and at least two urine albumin/creatinine ratio (UACR) were stratified into DKD stages: normoalbuminuria (UACR <30 mg/g), microalbuminuria (MI, UACR 30-299 mg/g), macroalbuminuria (MA, ≥300 mg/g) and renal impairment (RI, estimated glomerular filtration rate eGFR <60 mL/min per 1.73 m2). Factors associated with DKD stages were evaluated. Results Overall DKD prevalence (T2DM with MI, MA or RI) was high at 52.5%; 32.1% had MI, 5.3% had MA and 15.1% had RI. DKD prevalence within ethnic subpopulations was different: 52.2% of Chinese, 60.4% of Malays and 45.3% of Indians had DKD, respectively. Malays had a 1.42-fold higher DKD prevalence, while Indians had a 0.86-fold lower. Other independent risk factors were age, female gender, duration of diabetes and hypertension, HbA1c and body mass index. Conclusion The high prevalence of DKD and its interethnic differences suggest need for additional measures to optimize the care of T2DM at primary care to mitigate its progression.
Source Title: NEPHROLOGY
URI: https://scholarbank.nus.edu.sg/handle/10635/229293
ISSN: 13205358
14401797
DOI: 10.1111/nep.12379
Appears in Collections:Elements
Staff Publications

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
Ethnic disparity in prevalence of diabetic kidney Nephrology 20 (2015) 216 to223 Dr Matt.pdf129.05 kBAdobe PDF

CLOSED

Published

SCOPUSTM   
Citations

16
checked on Oct 1, 2022

Page view(s)

24
checked on Sep 29, 2022

Download(s)

1
checked on Sep 29, 2022

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.