Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/218825
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dc.titleHarmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration
dc.contributor.authorSmith, EE
dc.contributor.authorBiessels, GJ
dc.contributor.authorDe Guio, F
dc.contributor.authorde Leeuw, FE
dc.contributor.authorDuchesne, S
dc.contributor.authorDüring, M
dc.contributor.authorFrayne, R
dc.contributor.authorIkram, MA
dc.contributor.authorJouvent, E
dc.contributor.authorMacIntosh, BJ
dc.contributor.authorThrippleton, MJ
dc.contributor.authorVernooij, MW
dc.contributor.authorAdams, H
dc.contributor.authorBackes, WH
dc.contributor.authorBallerini, L
dc.contributor.authorBlack, SE
dc.contributor.authorChen, C
dc.contributor.authorCorriveau, R
dc.contributor.authorDeCarli, C
dc.contributor.authorGreenberg, SM
dc.contributor.authorGurol, ME
dc.contributor.authorIngrisch, M
dc.contributor.authorJob, D
dc.contributor.authorLam, BYK
dc.contributor.authorLauner, LJ
dc.contributor.authorLinn, J
dc.contributor.authorMcCreary, CR
dc.contributor.authorMok, VCT
dc.contributor.authorPantoni, L
dc.contributor.authorPike, GB
dc.contributor.authorRamirez, J
dc.contributor.authorReijmer, YD
dc.contributor.authorRomero, JR
dc.contributor.authorRopele, S
dc.contributor.authorRost, NS
dc.contributor.authorSachdev, PS
dc.contributor.authorScott, CJM
dc.contributor.authorSeshadri, S
dc.contributor.authorSharma, M
dc.contributor.authorSourbron, S
dc.contributor.authorSteketee, RME
dc.contributor.authorSwartz, RH
dc.contributor.authorvan Oostenbrugge, R
dc.contributor.authorvan Osch, M
dc.contributor.authorvan Rooden, S
dc.contributor.authorViswanathan, A
dc.contributor.authorWerring, D
dc.contributor.authorDichgans, M
dc.contributor.authorWardlaw, JM
dc.date.accessioned2022-04-11T03:04:10Z
dc.date.available2022-04-11T03:04:10Z
dc.date.issued2019-12-01
dc.identifier.citationSmith, EE, Biessels, GJ, De Guio, F, de Leeuw, FE, Duchesne, S, Düring, M, Frayne, R, Ikram, MA, Jouvent, E, MacIntosh, BJ, Thrippleton, MJ, Vernooij, MW, Adams, H, Backes, WH, Ballerini, L, Black, SE, Chen, C, Corriveau, R, DeCarli, C, Greenberg, SM, Gurol, ME, Ingrisch, M, Job, D, Lam, BYK, Launer, LJ, Linn, J, McCreary, CR, Mok, VCT, Pantoni, L, Pike, GB, Ramirez, J, Reijmer, YD, Romero, JR, Ropele, S, Rost, NS, Sachdev, PS, Scott, CJM, Seshadri, S, Sharma, M, Sourbron, S, Steketee, RME, Swartz, RH, van Oostenbrugge, R, van Osch, M, van Rooden, S, Viswanathan, A, Werring, D, Dichgans, M, Wardlaw, JM (2019-12-01). Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration. Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring 11 (1) : 191-204. ScholarBank@NUS Repository.
dc.identifier.issn2352-8729
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/218825
dc.description.abstractIntroduction: Many consequences of cerebrovascular disease are identifiable by magnetic resonance imaging (MRI), but variation in methods limits multicenter studies and pooling of data. The European Union Joint Program on Neurodegenerative Diseases (EU JPND) funded the HARmoNizing Brain Imaging MEthodS for VaScular Contributions to Neurodegeneration (HARNESS) initiative, with a focus on cerebral small vessel disease. Methods: Surveys, teleconferences, and an in-person workshop were used to identify gaps in knowledge and to develop tools for harmonizing imaging and analysis. Results: A framework for neuroimaging biomarker development was developed based on validating repeatability and reproducibility, biological principles, and feasibility of implementation. The status of current MRI biomarkers was reviewed. A website was created at www.harness-neuroimaging.org with acquisition protocols, a software database, rating scales and case report forms, and a deidentified MRI repository. Conclusions: The HARNESS initiative provides resources to reduce variability in measurement in MRI studies of cerebral small vessel disease.
dc.publisherWiley
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceElements
dc.subjectCerebrovascular disease
dc.subjectDementia
dc.subjectMagnetic resonance imaging
dc.subjectRadiology
dc.subjectStroke
dc.typeArticle
dc.date.updated2022-04-08T03:26:28Z
dc.contributor.departmentPHARMACOLOGY
dc.description.sourcetitleAlzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring
dc.description.volume11
dc.description.issue1
dc.description.page191-204
dc.published.statePublished
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