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https://doi.org/10.1038/s41598-022-06733-3
Title: | Prepregnancy body mass index and gestational weight gain are associated with maternal and infant adverse outcomes in Chinese women with gestational diabetes | Authors: | Zheng, QX Wang, HW Jiang, XM Lin, Y Liu, GH Pan, M Ge, L Chen, XQ Wu, JL Zhang, XY Pan, YQ He, HG |
Keywords: | Asians China Female Fetal Macrosomia Gestational Weight Gain Humans Infant, Newborn Obesity Pregnancy Pregnancy Outcome |
Issue Date: | 1-Dec-2022 | Publisher: | Springer Science and Business Media LLC | Citation: | Zheng, QX, Wang, HW, Jiang, XM, Lin, Y, Liu, GH, Pan, M, Ge, L, Chen, XQ, Wu, JL, Zhang, XY, Pan, YQ, He, HG (2022-12-01). Prepregnancy body mass index and gestational weight gain are associated with maternal and infant adverse outcomes in Chinese women with gestational diabetes. Scientific Reports 12 (1) : 2749-. ScholarBank@NUS Repository. https://doi.org/10.1038/s41598-022-06733-3 | Abstract: | The gestational weight gain (GWG) range of Chinese women with gestational diabetes mellitus (GDM) remains unclear. Our objective was to identify the ranges of GWG in Chinese women with GDM and to investigate the associations between prepregnancy body mass index (BMI), GWG and maternal-infant adverse outcomes. Cases of GDM women who delivered singletons from 2013 to 2018 in a public hospital were collected. Logistic regression analysis was used to assess the joint effects of prepregnancy BMI and GWG on maternal-infant adverse outcomes. Ultimately, 14,578 women were collected. The ranges of GWG in Chinese women with GDM were different from the National Academy of Medicine’s (NAM) recommendation. The ranges of GWG of Chinese women with GDM in the underweight, normal weight, overweight and obese groups were 5.95–21.95 kg, 4.23–21.83 kg, 0.88–21.12 kg and − 1.76 to 19.95 kg, respectively. The risks of large for gestational age (LGA), macrosomia and caesarean delivery were significantly increased with the increasing prepregnancy BMI. Furthermore, the risks of LGA, macrosomia and caesarean delivery were significantly higher in the normal weight group with a GWG higher than the NAM recommendation. Similarly, in the overweight group with a GWG higher than the NAM recommendation, the risks of LGA were significantly higher, while the risks of macrosomia were significantly lower. Overall, we determined the range of GWG in different prepregnancy BMI groups. And GDM women with high prepregnancy BMI and excessive GWG were associated with the higher risks of maternal-infants adverse outcomes in China. | Source Title: | Scientific Reports | URI: | https://scholarbank.nus.edu.sg/handle/10635/217537 | ISSN: | 2045-2322 | DOI: | 10.1038/s41598-022-06733-3 |
Appears in Collections: | Staff Publications Elements |
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