Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.sleh.2019.10.009
Title: Antenatal sleep quality associated with perinatal outcomes in women of advanced maternal age
Authors: Lee, Pei Yu
Liu, Li Hui
Ho, Cowan
Ang, Aloysius Jian Feng
Huang, Hui Xin
Teoh, Oon-Hoe 
Tan, Kok-Hian 
Lee, Yung Seng 
Yap, Fabian 
Gooley, Joshua J
Chan, Shiao-Yng
Cai, Shirong 
Keywords: Science & Technology
Life Sciences & Biomedicine
Clinical Neurology
Neurosciences & Neurology
Pregnancy
Birth outcomes
Advanced maternal age
Sleep quality
PREGNANCY OUTCOMES
ADVERSE OUTCOMES
DISTURBED SLEEP
PRETERM BIRTH
DURATION
INFLAMMATION
INTERLEUKIN-6
DEPRIVATION
DELIVERY
FATIGUE
Issue Date: 1-Feb-2020
Publisher: ELSEVIER
Citation: Lee, Pei Yu, Liu, Li Hui, Ho, Cowan, Ang, Aloysius Jian Feng, Huang, Hui Xin, Teoh, Oon-Hoe, Tan, Kok-Hian, Lee, Yung Seng, Yap, Fabian, Gooley, Joshua J, Chan, Shiao-Yng, Cai, Shirong (2020-02-01). Antenatal sleep quality associated with perinatal outcomes in women of advanced maternal age. SLEEP HEALTH 6 (1) : 60-64. ScholarBank@NUS Repository. https://doi.org/10.1016/j.sleh.2019.10.009
Abstract: Objectives: The increasing prevalence of advanced maternal age (AMA) coupled with poor sleep quality among pregnant women makes it important to study their association with perinatal outcomes. However, little is known about the interaction of AMA and maternal antenatal sleep on perinatal outcomes. Here, we examined whether associations between AMA and perinatal outcomes are modified by antenatal sleep quality. Participants: Data were collected from 446 women, with a singleton pregnancy and no pregnancy complications, who participated in the Growing Up in Singapore Towards healthy Outcomes (GUSTO) birth cohort study. Measurements: Participants completed the Pittsburgh Sleep Quality Index (PSQI) at 26-28 weeks gestation and had perinatal outcome data collected upon delivery. Interactions between AMA and maternal sleep quality on perinatal outcomes were investigated and where significant, analyses were further stratified by maternal age. All analyses were adjusted for maternal BMI at 26-28 weeks gestation, ethnicity, and maternal education. Results: Neonates of mothers of AMA and poor sleep quality (PSQI score >5) had increased odds of stay in the neonatal intensive care unit (adjusted odds ratio = 3.53, 95% CI: −1.21 to 10.27) and shorter birth length (adjusted mean difference = −1.05 cm, 95% CI: −1.82 to −0.20), as compared with women of AMA and good sleep quality (PSQI score ≤5). In women <35 years, sleep quality did not associate with perinatal outcomes. Conclusion: Poor sleep quality in women of AMA was associated with neonatal health outcomes. Improving maternal antenatal sleep may potentially improve perinatal outcomes in offspring of women of AMA.
Source Title: SLEEP HEALTH
URI: https://scholarbank.nus.edu.sg/handle/10635/216237
ISSN: 23527218
23527226
DOI: 10.1016/j.sleh.2019.10.009
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