Please use this identifier to cite or link to this item: https://doi.org/10.3389/fmicb.2019.01447
Title: Genomic insights into the distribution and evolution of group B streptococcus
Authors: Chen, S.L. 
Keywords: Foodborne disease
Genomics
Group B Streptococcus
Molecular epidemiology
Review
Streptococcus agalactiae
Whole genome sequencing
Issue Date: 2019
Publisher: Frontiers Media S.A.
Citation: Chen, S.L. (2019). Genomic insights into the distribution and evolution of group B streptococcus. Frontiers in Microbiology 10 (JUN) : 1447. ScholarBank@NUS Repository. https://doi.org/10.3389/fmicb.2019.01447
Rights: Attribution 4.0 International
Abstract: Streptococcus agalactiae, also known as Group B Streptococcus (GBS), is a bacteria with truly protean biology. It infects a variety of hosts, among which the most commonly studied are humans, cattle, and fish. GBS holds a singular position in the history of bacterial genomics, as it was the substrate used to describe one of the first major conceptual advances of comparative genomics, the idea of the pan-genome. In this review, I describe a brief history of GBS and the major contributions of genomics to understanding its genome plasticity and evolution as well as its molecular epidemiology, focusing on the three hosts mentioned above. I also discuss one of the major recent paradigm shifts in our understanding of GBS evolution and disease burden: foodborne GBS can cause invasive infections in humans. © 2007 - 2019 Frontiers Media S.A. All Rights Reserved.
Source Title: Frontiers in Microbiology
URI: https://scholarbank.nus.edu.sg/handle/10635/213736
ISSN: 1664302X
DOI: 10.3389/fmicb.2019.01447
Rights: Attribution 4.0 International
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