Please use this identifier to cite or link to this item: https://doi.org/10.1038/s41598-018-38331-7
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dc.titleLamina Cribrosa Curvature in Healthy Korean Eyes
dc.contributor.authorLee, S.H.
dc.contributor.authorKim, T.-W.
dc.contributor.authorLee, E.J.
dc.contributor.authorGirard, M.J.A.
dc.contributor.authorMari, J.M.
dc.date.accessioned2022-01-07T03:50:18Z
dc.date.available2022-01-07T03:50:18Z
dc.date.issued2019
dc.identifier.citationLee, S.H., Kim, T.-W., Lee, E.J., Girard, M.J.A., Mari, J.M. (2019). Lamina Cribrosa Curvature in Healthy Korean Eyes. Scientific Reports 9 (1) : 1756. ScholarBank@NUS Repository. https://doi.org/10.1038/s41598-018-38331-7
dc.identifier.issn2045-2322
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/213246
dc.description.abstractGiven that posterior bowing of the lamina cribrosa (LC) is a principle event in the development of glaucomatous damage, assessment of the LC morphology may have clinical utility in diagnosing and managing glaucoma patients. LC curvature has been suggested as an index to evaluate the LC morphology. To apply LC morphology in clinical practice, it is necessary to know normal profiles of LC curvature in healthy population. This study was performed to investigate the characteristics of LC curvature in healthy eyes using enhanced depth imaging spectral-domain optical coherence tomography in a total of 250 eyes of 125 healthy Korean subjects. The lamina cribrosa curvature index (LCCI) values at seven locations spaced equidistantly across the vertical optic disc diameter were measured on serial horizontal B-scan images. The mean value of the seven measurements was defined as the average LCCI. The average LCCI was 7.46 ± 1.22 (range, 4.29–10.48) and did not differ significantly between the right and left eyes. There was a strong inter-eye correlation within subjects. LCCI was significantly larger in eyes with shorter axial length (P < 0.001). The observed range of LCCI in healthy subjects may be used as a reference for evaluating LC curvature in glaucomatous eyes. © 2019, The Author(s).
dc.publisherNature Publishing Group
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourceScopus OA2019
dc.typeArticle
dc.contributor.departmentDEPT OF BIOMEDICAL ENGINEERING
dc.description.doi10.1038/s41598-018-38331-7
dc.description.sourcetitleScientific Reports
dc.description.volume9
dc.description.issue1
dc.description.page1756
dc.published.statePublished
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