Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/212715
Title: GREEN AND EFFICIENT PRODUCTION OF HIGH-VALUE FINE CHEMICALS FROM RENEWABLE RESOURCES THROUGH CASCADE BIOTRANSFORMATION
Authors: BENEDICT RYAN LUKITO
ORCID iD:   orcid.org/0000-0001-9285-1686
Keywords: enzyme catalysis, cascade reaction, biotransformation, asymmetric synthesis, sustainable chemistry, fine chemicals
Issue Date: 7-Aug-2019
Citation: BENEDICT RYAN LUKITO (2019-08-07). GREEN AND EFFICIENT PRODUCTION OF HIGH-VALUE FINE CHEMICALS FROM RENEWABLE RESOURCES THROUGH CASCADE BIOTRANSFORMATION. ScholarBank@NUS Repository.
Abstract: Enzyme catalysis has received great attentions for green and sustainable manufacturing of high-value enantiopure chemicals in attribution to its benign reaction conditions, non-toxicity, high regio-, chemo-, and stereoselectivity, as well as the ability of performing multi-step synthesis in one-pot. Despite of the success and great achievements, enzyme catalysis still encounter several major drawbacks, such as lack of non-natural pathway, high yielding transformation, and robust biocatalyst to give sustainable manufacturing process, as well its practical application for the downstream processing. Furthermore, substrate and/or product inhibition in biocatalysis is still inevitable. To address these gaps, novel and efficient artificial cascade biocatalysis pathways from renewable and simple resources were developed. These artificial cascade biotransformation of L-phenylalanine, glycerol, or glucose provides high-yielding, sustainable, and potentially practical synthesis of high-value natural chemicals.
URI: https://scholarbank.nus.edu.sg/handle/10635/212715
Appears in Collections:Ph.D Theses (Open)

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
LukitoBR.pdf3.1 MBAdobe PDF

OPEN

NoneView/Download

Page view(s)

22
checked on Sep 22, 2022

Download(s)

3
checked on Sep 22, 2022

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.