Please use this identifier to cite or link to this item:
https://doi.org/10.3390/ijerph16245148
DC Field | Value | |
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dc.title | Diet, secondhand smoke, and glycated hemoglobin (HbA1c) levels among Singapore Chinese adults | |
dc.contributor.author | Moore, B.F. | |
dc.contributor.author | Butler, L.M. | |
dc.contributor.author | Bachand, A.M. | |
dc.contributor.author | Salim, A. | |
dc.contributor.author | Reynolds, S.J. | |
dc.contributor.author | Wang, R. | |
dc.contributor.author | Nelson, T.L. | |
dc.contributor.author | Peel, J.L. | |
dc.contributor.author | Murphy, S.E. | |
dc.contributor.author | Koh, W.-P. | |
dc.contributor.author | Yuan, J.-M. | |
dc.contributor.author | Clark, M.L. | |
dc.date.accessioned | 2021-12-06T04:19:09Z | |
dc.date.available | 2021-12-06T04:19:09Z | |
dc.date.issued | 2019 | |
dc.identifier.citation | Moore, B.F., Butler, L.M., Bachand, A.M., Salim, A., Reynolds, S.J., Wang, R., Nelson, T.L., Peel, J.L., Murphy, S.E., Koh, W.-P., Yuan, J.-M., Clark, M.L. (2019). Diet, secondhand smoke, and glycated hemoglobin (HbA1c) levels among Singapore Chinese adults. International Journal of Environmental Research and Public Health 16 (24) : 5148. ScholarBank@NUS Repository. https://doi.org/10.3390/ijerph16245148 | |
dc.identifier.issn | 1661-7827 | |
dc.identifier.uri | https://scholarbank.nus.edu.sg/handle/10635/209500 | |
dc.description.abstract | The combination of poor diet and exposure to secondhand smoke may increase hemoglobin A1c (HbA1c) levels, but few studies have explored this interaction. We explored an interaction among 574 never-smoking adults from the Singapore Chinese Health Study. At baseline (age 59 ± 8 years), intakes of omega-3 polyunsaturated fatty acids, vitamin C, vitamin E and fiber were estimated using a modified food frequency questionnaire. At follow-up (age 64 ± 9 years), HbA1c and cotinine were measured. A product term between cotinine (above or below the median value) and each nutrient (high or low intake) was included in separate linear regression models with HbA1c as the outcome. HbA1c among those with high cotinine and low omega-3 polyunsaturated fatty acids intakes were higher than would be expected due to the individual effects alone (p-for-interaction = 0.05). Among those with lower intakes of omega-3 polyunsaturated fatty acids, high cotinine levels were associated with 0.54% higher HbA1c levels (95% confidence interval [CI]: 0.02, 1.06). Conversely, among those with higher intakes of omega-3 polyunsaturated fatty acids, HbA1c differ not differ by exposure (?0.09%; 95% CI: ?0.45, 0.30). No evidence of interaction was observed for other nutrients. Diets high in omega-3 polyunsaturated fatty acids may ameliorate secondhand smoke-induced increases in HbA1c. © 2019 by the authors. Licensee MDPI, Basel, Switzerland. | |
dc.publisher | MDPI AG | |
dc.rights | Attribution 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.source | Scopus OA2019 | |
dc.subject | Antioxidants | |
dc.subject | Cotinine | |
dc.subject | Diet | |
dc.subject | HbA1c | |
dc.subject | Interaction | |
dc.subject | Omega-3 polyunsaturated fatty acids | |
dc.type | Article | |
dc.contributor.department | DUKE-NUS MEDICAL SCHOOL | |
dc.description.doi | 10.3390/ijerph16245148 | |
dc.description.sourcetitle | International Journal of Environmental Research and Public Health | |
dc.description.volume | 16 | |
dc.description.issue | 24 | |
dc.description.page | 5148 | |
Appears in Collections: | Staff Publications Elements |
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