Please use this identifier to cite or link to this item: https://doi.org/10.1159/000452218
Title: Establishing Prenatal Surgery for Myelomeningocele in Asia: The Singapore Consensus
Authors: Wataganara, Tuangsit
Seshadri, Suresh
Leung, Tak Yeung
Matter, Citra
Ngerncham, Monawat
Triyasunant, Namtip
Mali, Padmakar Vidyadhar 
Biswas, Agnhitori 
Nawapun, Katika
Phithakwatchara, Nisarat
Flake, Alan W
Johnson, Mark P
Biswas, Arijit 
Choolani, Mahesh 
Keywords: Science & Technology
Life Sciences & Biomedicine
Obstetrics & Gynecology
Myelomeningocele
Prenatal surgery
Prenatal fetal therapy
Fetal therapy centers
NEURAL-TUBE DEFECTS
POPULATION-BASED SURVEY
SPINA-BIFIDA
BIRTH-DEFECTS
SHANXI PROVINCE
FETAL SURGERY
DOWN-SYNDROME
PREVALENCE
REPAIR
RISK
Issue Date: 1-Jan-2017
Publisher: KARGER
Citation: Wataganara, Tuangsit, Seshadri, Suresh, Leung, Tak Yeung, Matter, Citra, Ngerncham, Monawat, Triyasunant, Namtip, Mali, Padmakar Vidyadhar, Biswas, Agnhitori, Nawapun, Katika, Phithakwatchara, Nisarat, Flake, Alan W, Johnson, Mark P, Biswas, Arijit, Choolani, Mahesh (2017-01-01). Establishing Prenatal Surgery for Myelomeningocele in Asia: The Singapore Consensus. FETAL DIAGNOSIS AND THERAPY 41 (3) : 161-178. ScholarBank@NUS Repository. https://doi.org/10.1159/000452218
Abstract: Objectives: The Management of Myelomeningocele Study (MOMS Trial) has inspired many fetal therapy centers (FTCs) to offer open fetal surgery for myelomeningocele (MMC). This is an initial effort to create a candidate model that can be applicable to many parts of Asia. Material and Methods: A limited selection of specialists from 4 established FTCs in Thailand, Hong Kong, India, and Singapore met for a round table discussion. Experts from Children's Hospital of Philadelphia (CHOP) involved in the Trial moderated the session. The practice suggestions in this statement were from a targeted literature review and expert opinion. Results: A high prevalence of MMC in Asia supports an effort to adopt the procedure, but only in established FTCs with good maternal and neonatal ancillary supports. The falling incidence of MMCs may affect case volume and maintenance of skill. A regional approach was recommended. Fetal benefits have to be weighed against maternal risks, with a consideration of recent outcome data from the endoscopic approach. Responsible FTCs need standardized diagnosis and management, with their long-term outcome data available for an audit. Conclusions: It is envisaged that the information presented by this multidisciplinary team would be useful for FTCs in Asia or elsewhere that plan to establish more advanced fetal care in the future.
Source Title: FETAL DIAGNOSIS AND THERAPY
URI: https://scholarbank.nus.edu.sg/handle/10635/208340
ISSN: 10153837
14219964
DOI: 10.1159/000452218
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