Please use this identifier to cite or link to this item: https://doi.org/10.1136/bmjopen-2017-020512
DC FieldValue
dc.titleHealth-related quality of life in Asian patients with breast cancer: a systematic review
dc.contributor.authorHo, Peh Joo
dc.contributor.authorGernaat, Sofie AM
dc.contributor.authorHartman, Mikael
dc.contributor.authorVerkooijen, Helena M
dc.date.accessioned2021-11-26T04:10:07Z
dc.date.available2021-11-26T04:10:07Z
dc.date.issued2018-04-01
dc.identifier.citationHo, Peh Joo, Gernaat, Sofie AM, Hartman, Mikael, Verkooijen, Helena M (2018-04-01). Health-related quality of life in Asian patients with breast cancer: a systematic review. BMJ OPEN 8 (4). ScholarBank@NUS Repository. https://doi.org/10.1136/bmjopen-2017-020512
dc.identifier.issn20446055
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/208272
dc.description.abstractObjective To summarise the evidence on determinants of health-related quality of life (HRQL) in Asian patients with breast cancer. Design Systematic review conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations and registered with PROSPERO (CRD42015032468). Methods According to the PRISMA guidelines, databases of MEDLINE (PubMed), Embase and PsycINFO were systematically searched using the following terms and synonyms: breast cancer, quality of life and Asia. Articles reporting on HRQL using EORTC-QLQ-C30, EORTC-QLQ-BR23, FACT-G and FACT-B questionnaires in Asian patients with breast cancer were eligible for inclusion. The methodological quality of each article was assessed using the quality assessment scale for cross-sectional studies or the Newcastle-Ottawa Quality Assessment Scale for cohort studies. Results Fifty-seven articles were selected for this qualitative synthesis, of which 43 (75%) were cross-sectional and 14 (25%) were longitudinal studies. Over 75 different determinants of HRQL were studied with either the EORTC or FACT questionnaires. Patients with comorbidities, treated with chemotherapy, with less social support and with more unmet needs have poorer HRQL. HRQL improves over time. Discordant results in studies were found in the association of age, marital status, household income, type of surgery, radiotherapy and hormone therapy and unmet sexuality needs with poor global health status or overall well-being. Conclusions In Asia, patients with breast cancer, in particular those with other comorbidities and those treated with chemotherapy, with less social support and with more unmet needs, have poorer HRQL. Appropriate social support and meeting the needs of patients may improve patients' HRQL.
dc.language.isoen
dc.publisherBMJ PUBLISHING GROUP
dc.sourceElements
dc.subjectScience & Technology
dc.subjectLife Sciences & Biomedicine
dc.subjectMedicine, General & Internal
dc.subjectGeneral & Internal Medicine
dc.subjectCHINESE WOMEN
dc.subjectUNMET NEEDS
dc.subjectFACT-B
dc.subjectEUROPEAN-ORGANIZATION
dc.subjectCONSERVATION THERAPY
dc.subjectMENOPAUSAL SYMPTOMS
dc.subjectSOCIAL SUPPORT
dc.subjectKOREAN VERSION
dc.subjectMEDIATING ROLE
dc.subjectEORTC QLQ-C30
dc.typeReview
dc.date.updated2021-11-25T16:32:00Z
dc.contributor.departmentEPIDEMIOLOGY & PUBLIC HEALTH
dc.description.doi10.1136/bmjopen-2017-020512
dc.description.sourcetitleBMJ OPEN
dc.description.volume8
dc.description.issue4
dc.published.statePublished
Appears in Collections:Staff Publications
Elements

Show simple item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
Health-related quality of life in Asian patients with breast cancer a systematic review.pdfPublished version806.14 kBAdobe PDF

OPEN

PublishedView/Download

SCOPUSTM   
Citations

57
checked on Dec 2, 2022

Page view(s)

89
checked on Dec 1, 2022

Download(s)

2
checked on Dec 1, 2022

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.