Please use this identifier to cite or link to this item: https://doi.org/10.1007/s00520-019-04848-4
Title: Systematic review of basic oral care for the management of oral mucositis in cancer patients and clinical practice guidelines
Authors: HSU LING CATHERINE HONG 
Gueiros, Luiz Alcino
Fulton, Janet S
Cheng Kin Fong Karis 
Kandwal, Abhishek
Galiti, Dimitra
Fall-Dickson, Jane M
Johansen, Jorgen
Ameringer, Suzanne
Kataoka, Tomoko
Weikel, Dianna
Eilers, June
Ranna, Vinasha
Vaddi, Anusha
Lalla, Rajesh V
Bossi, Paolo
Elad, Sharon
Keywords: Science & Technology
Life Sciences & Biomedicine
Oncology
Health Care Sciences & Services
Rehabilitation
Basic oral care
Chlorhexidine
Oral mucositis
Sodium bicarbonate
Saline
Patient education
Dental care
Guidelines
Cancer
STEM-CELL TRANSPLANTATION
DOUBLE-BLIND
ACUTE-LEUKEMIA
NECK-CANCER
MARROW-TRANSPLANTATION
MOUTH CARE
CHLORHEXIDINE PROPHYLAXIS
POVIDONE-IODINE
HEALTH CARE
CHEMOTHERAPY
Issue Date: 1-Oct-2019
Publisher: SPRINGER
Citation: HSU LING CATHERINE HONG, Gueiros, Luiz Alcino, Fulton, Janet S, Cheng Kin Fong Karis, Kandwal, Abhishek, Galiti, Dimitra, Fall-Dickson, Jane M, Johansen, Jorgen, Ameringer, Suzanne, Kataoka, Tomoko, Weikel, Dianna, Eilers, June, Ranna, Vinasha, Vaddi, Anusha, Lalla, Rajesh V, Bossi, Paolo, Elad, Sharon (2019-10-01). Systematic review of basic oral care for the management of oral mucositis in cancer patients and clinical practice guidelines. SUPPORTIVE CARE IN CANCER 27 (10) : 3949-3967. ScholarBank@NUS Repository. https://doi.org/10.1007/s00520-019-04848-4
Abstract: Purpose: The aim of this study was to update the clinical practice guidelines for the use of basic oral care (BOC) interventions for the prevention and/or treatment of oral mucositis (OM). Methods: A systematic review was conducted by the Mucositis Study Group of the Multinational Association of Supportive Care in Cancer/International Society for Oral Oncology (MASCC/ISOO). The body of evidence for each intervention in each cancer treatment setting was assigned an evidence level. The findings were added to the database used to develop the 2013 MASCC/ISOO clinical practice guidelines. Based on the evidence level, one of the following three guideline determinations was possible: Recommendation, Suggestion, No guideline possible. Results: A total of 17 new papers across six interventions were examined and merged with a previous database. Based on the literature, the following guidelines were possible. The panel suggests that the implementation of multi-agent combination oral care protocols is beneficial for the prevention of OM during chemotherapy, head and neck (H&N) radiation therapy (RT), and hematopoietic stem cell transplantation (Level of Evidence III). The panel suggests that chlorhexidine not be used to prevent OM in patients undergoing H&N RT (Level of Evidence III). No guideline was possible for professional oral care, patient education, saline, and sodium bicarbonate, and expert opinion complemented these guidelines. Conclusions: The evidence supports the use of multi-agent combination oral care protocols in the specific populations listed above. Additional well-designed research is needed on the other BOC interventions prior to guideline formulation.
Source Title: SUPPORTIVE CARE IN CANCER
URI: https://scholarbank.nus.edu.sg/handle/10635/207362
ISSN: 0941-4355
1433-7339
DOI: 10.1007/s00520-019-04848-4
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