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dc.titleCohort profile: The Singapore Breast Cancer Cohort (SGBCC), a multi-center breast cancer cohort for evaluation of phenotypic risk factors and genetic markers
dc.contributor.authorHo, Peh Joo
dc.contributor.authorYeoh, Yen Shing
dc.contributor.authorMiao, Hui
dc.contributor.authorLim, Swee Ho
dc.contributor.authorTan, Ern Yu
dc.contributor.authorTan, Benita Kiat Tee
dc.contributor.authorTan, Veronique Kiak Mien
dc.contributor.authorTan, Su Ming
dc.contributor.authorYong, Wei Sean
dc.contributor.authorWong, Fuh Yong
dc.contributor.authorMadhukumar, Preetha
dc.contributor.authorChan, Ching Wan
dc.contributor.authorIau, Philip Tsau Choong
dc.contributor.authorLee, Soo Chin
dc.contributor.authorPutti, Thomas
dc.contributor.authorBuhari, Shaik Ahmad
dc.contributor.authorLee, Jin Yee
dc.contributor.authorLim, Geok Hoon
dc.contributor.authorWoo, Evan
dc.contributor.authorYan, Zhiyan
dc.contributor.authorChan, Patrick Mun Yew
dc.contributor.authorChen, Juliana Jia Chuan
dc.contributor.authorLu, Sarah Qinghui
dc.contributor.authorDent, Rebecca
dc.contributor.authorLee, Wai Peng
dc.contributor.authorMok, Chi Wei
dc.contributor.authorSeah, Jaime Chin Mui
dc.contributor.authorSim, Xueling
dc.contributor.authorvan Dam, Rob Martinus
dc.contributor.authorChia, Kee Seng
dc.contributor.authorLi, Jingmei
dc.contributor.authorHartman, Mikael
dc.identifier.citationHo, Peh Joo, Yeoh, Yen Shing, Miao, Hui, Lim, Swee Ho, Tan, Ern Yu, Tan, Benita Kiat Tee, Tan, Veronique Kiak Mien, Tan, Su Ming, Yong, Wei Sean, Wong, Fuh Yong, Madhukumar, Preetha, Chan, Ching Wan, Iau, Philip Tsau Choong, Lee, Soo Chin, Putti, Thomas, Buhari, Shaik Ahmad, Lee, Jin Yee, Lim, Geok Hoon, Woo, Evan, Yan, Zhiyan, Chan, Patrick Mun Yew, Chen, Juliana Jia Chuan, Lu, Sarah Qinghui, Dent, Rebecca, Lee, Wai Peng, Mok, Chi Wei, Seah, Jaime Chin Mui, Sim, Xueling, van Dam, Rob Martinus, Chia, Kee Seng, Li, Jingmei, Hartman, Mikael (2021-04-26). Cohort profile: The Singapore Breast Cancer Cohort (SGBCC), a multi-center breast cancer cohort for evaluation of phenotypic risk factors and genetic markers. PLOS ONE 16 (4). ScholarBank@NUS Repository.
dc.description.abstractThis article aims to provide a detailed description of the Singapore Breast Cancer Cohort (SGBCC), an ongoing multi-ethnic cohort established with the overarching goal to identify genetic markers for breast cancer risk, prognosis and treatment response, as well as to understand the ethnic differences in disease risk and outcome in an Asian setting. The cohort comprises of breast cancer patients aged 21 years and above from six public hospitals which diagnose and treat nearly 76% breast cancer cases in Singapore. Self-reported data on sociodemographic and lifestyle, reproductive risk factors, medical history and family history of breast or ovarian cancer is collected using a structured questionnaire. Clinical data on tumour characteristics, and treatment modalities are obtained through medical record. Bio-specimens (blood or saliva) is collected at recruitment. Follow-up on survival information is done through routine linkage with the Registry of Births and Deaths. As of 31 December 2016, 7,768 subjects have been recruited to the study with 76% subjects contributed bio-specimens. The SGBCC provides a valuable platform which offers a unique, large and rich resource for new research ideas on breast cancer related phenotypic risk factors and genetic markers.
dc.subjectScience & Technology
dc.subjectMultidisciplinary Sciences
dc.subjectScience & Technology - Other Topics
dc.contributor.departmentDEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
dc.contributor.departmentDEPT OF SURGERY
dc.contributor.departmentDUKE-NUS MEDICAL SCHOOL
dc.description.sourcetitlePLOS ONE
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