Please use this identifier to cite or link to this item: https://doi.org/10.3390/nu13020408
Title: Breastfeeding Duration and Development of Dysglycemia in Women Who Had Gestational Diabetes Mellitus: Evidence from the GUSTO Cohort Study
Authors: AKURASSA HEWAGE SUMALI SUBHASHINI HEWAGE 
KOH XIN YU, HAZEL 
SOH SHU E 
PANG WEI WEI 
Fok, Doris
Cai Shirong 
MUELLER-RIEMENSCHNEIDER FALK 
FABIAN YAP KOK PENG 
TAN KOK HIAN 
CHUA MEI CHIEN 
Lim, Sok Bee
Godfrey, Keith M
COLEGA MARJORELEE TABALDO 
CHONG YAP SENG 
CHAN SHIAO-YNG 
Yoong, Joanne
MARY CHONG FOONG FONG 
Keywords: Breastfeeding
gestational diabetes
type 2 diabetes risk
prediabetes risk
Issue Date: 28-Jan-2021
Publisher: MDPI AG
Citation: AKURASSA HEWAGE SUMALI SUBHASHINI HEWAGE, KOH XIN YU, HAZEL, SOH SHU E, PANG WEI WEI, Fok, Doris, Cai Shirong, MUELLER-RIEMENSCHNEIDER FALK, FABIAN YAP KOK PENG, TAN KOK HIAN, CHUA MEI CHIEN, Lim, Sok Bee, Godfrey, Keith M, COLEGA MARJORELEE TABALDO, CHONG YAP SENG, CHAN SHIAO-YNG, Yoong, Joanne, MARY CHONG FOONG FONG (2021-01-28). Breastfeeding Duration and Development of Dysglycemia in Women Who Had Gestational Diabetes Mellitus: Evidence from the GUSTO Cohort Study. Nutrients 13 (2) : 408-408. ScholarBank@NUS Repository. https://doi.org/10.3390/nu13020408
Abstract: (1) Background: Breastfeeding has been shown to support glucose homeostasis in women after a pregnancy complicated by gestational diabetes mellitus (GDM) and is potentially effective at reducing long-term diabetes risk. (2) Methods: Data from the Growing Up in Singapore Towards healthy Outcomes (GUSTO) study were analyzed to understand the influence of breastfeeding duration on long-term dysglycemia (prediabetes and diabetes) risk in women who had GDM in the index pregnancy. GDM and dysglycemia four to seven years postpartum were determined by the oral glucose tolerance test(OGTT). A Poisson regression model with a robust error variance was used to estimate incidence rate ratios (IRRs) for dysglycemia four to seven years post-delivery according to groupings of the duration of any breastfeeding(<1,≥1to<6,and≥6months). (3)Results: Women who had GDM during the index pregnancy and complete breastfeeding information and OGTT four to seven years postpartum were included in this study (n = 116). Fifty-one women (44%) had postpartum dysglycemia. Unadjusted IRRs showed an inverse association between dysglycemia risk and≥1monthto<6months(IRR0.91;95%confidenceinterval[CI]0.57,1.43;p=0.68)and≥6months (IRR0.50;95%CI0.27,0.91;p=0.02)breastfeeding compared to<1monthofanybreastfeeding. After adjusting for key confounders, the IRR for the≥6 months group remained significant (IRR 0.42; 95% CI 0.22, 0.80; p = 0.008). (4) Conclusions: Our results suggest that any breastfeeding of six months or longer may reduce long-term dysglycemia risk in women with a history of GDM in an Asian setting. Breastfeeding has benefits for mothers beyond weight loss, particularly for those with GDM.
Source Title: Nutrients
URI: https://scholarbank.nus.edu.sg/handle/10635/186101
ISSN: 2072-6643
DOI: 10.3390/nu13020408
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