Please use this identifier to cite or link to this item: https://doi.org/10.1186/s40246-017-0116-4
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dc.titleFalling giants and the rise of gene editing: Ethics, private interests and the public good Ruth Chadwick
dc.contributor.authorCapps, B
dc.contributor.authorChadwick, R
dc.contributor.authorJoly, Y
dc.contributor.authorMulvihill, J.J
dc.contributor.authorLysaght, T
dc.contributor.authorZwart, H
dc.date.accessioned2020-11-17T06:35:02Z
dc.date.available2020-11-17T06:35:02Z
dc.date.issued2017
dc.identifier.citationCapps, B, Chadwick, R, Joly, Y, Mulvihill, J.J, Lysaght, T, Zwart, H (2017). Falling giants and the rise of gene editing: Ethics, private interests and the public good Ruth Chadwick. Human Genomics 11 (1) : 20. ScholarBank@NUS Repository. https://doi.org/10.1186/s40246-017-0116-4
dc.identifier.issn1473-9542
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/183543
dc.description.abstractThis paper considers the tensions created in genomic research by public and private for-profit ideals. Our intent is to strengthen the public good at a time when doing science is strongly motivated by market possibilities and opportunities. Focusing on the emergence of gene editing, and in particular CRISPR, we consider how commercialisation encourages hype and hope - a sense that only promise and idealism can achieve progress. At this rate, genomic research reinforces structures that promote, above all else, private interests, but that may attenuate conditions for the public good of science. In the first part, we situate genomics using the aphorism that 'on the shoulders of giants we see farther'; these giants are infrastructures and research cultures rather than individual 'heroes' of science. In this respect, private initiatives are not the only pivot for successful discovery, and indeed, fascination in those could impinge upon the fundamental role of public-supported discovery. To redress these circumstances, we define the extent to which progress presupposes research strategies that are for the public good. In the second part, we use a 'falling giant' narrative to illustrate the risks of over-indulging for-profit initiatives. We therefore offer a counterpoint to commercialised science, using three identifiable 'giants' - scientists, publics and cultures - to illustrate how the public good contributes to genomic discovery. © 2017 The Author(s).
dc.publisherHenry Stewart Publications
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceUnpaywall 20201031
dc.subjectbiobank
dc.subjectclustered regularly interspaced short palindromic repeat
dc.subjectethics
dc.subjectgene editing
dc.subjectgenomics
dc.subjecthuman
dc.subjecthuman genome project
dc.subjectmarket
dc.subjectnarrative
dc.subjectprofit
dc.subjectscientist
dc.subjectshoulder
dc.subjecttension
dc.subjectgene editing
dc.subjectinterpersonal communication
dc.subjectmedical genetics
dc.subjectmedical research
dc.subjectprocedures
dc.subjectpublic opinion
dc.subjectBiomedical Research
dc.subjectCommunication
dc.subjectGene Editing
dc.subjectGenetics, Medical
dc.subjectGenomics
dc.subjectHumans
dc.subjectPublic Opinion
dc.typeReview
dc.contributor.departmentDEAN'S OFFICE (MEDICINE)
dc.description.doi10.1186/s40246-017-0116-4
dc.description.sourcetitleHuman Genomics
dc.description.volume11
dc.description.issue1
dc.description.page20
dc.published.statePublished
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