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https://doi.org/10.3390/cancers2010032
Title: | Oxidative stress and exhaled breath analysis: A promising tool for detection of lung Cancer | Authors: | Chan, H.P Lewis, C Thomas, P.S |
Keywords: | cytokine gold nanoparticle nitric oxide protein derivative reactive oxygen metabolite tumor marker volatile organic compound analytic method analyzer biosensor biotechnology breath analysis chemoluminescence colorimetry diagnostic accuracy diagnostic value disease marker DNA damage early diagnosis exhaled breath condensate expired air gas analysis gene mutation human ion mobility spectrometry lipid peroxidation liquid phase analysis lung cancer lung non small cell cancer oxidative stress reproducibility respiratory tract inflammation respiratory tract parameters review sensitivity and specificity |
Issue Date: | 2010 | Citation: | Chan, H.P, Lewis, C, Thomas, P.S (2010). Oxidative stress and exhaled breath analysis: A promising tool for detection of lung Cancer. Cancers 2 (1) : 32-42. ScholarBank@NUS Repository. https://doi.org/10.3390/cancers2010032 | Rights: | Attribution 4.0 International | Abstract: | Lung cancer is one of the few neoplasia in which the principal aetiology is known, with cigarette smoke donating a considerable oxidative burden to the lungs. This may be part of the aetiology of lung cancer, but the neoplastic process is also associated with increased oxidative stress. Nonetheless, it is difficult to study the mechanisms behind the induction of lung cancer in smokers, but newer techniques of breath analysis targeting markers of oxidative stress and anti-oxidant capacity show promise in unravelling some of the pathways. This review highlights recent developments in the assessment of oxidative stress by non-invasive methods of breath analysis which are becoming powerful research techniques with possible clinical applications. © 2010 by the authors. | Source Title: | Cancers | URI: | https://scholarbank.nus.edu.sg/handle/10635/182060 | ISSN: | 20726694 | DOI: | 10.3390/cancers2010032 | Rights: | Attribution 4.0 International |
Appears in Collections: | Elements Staff Publications |
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