Please use this identifier to cite or link to this item: https://doi.org/10.1155/2014/620423
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dc.titleOne patient, two uncommon B-cell neoplasms: Solitary plasmacytoma following complete remission from intravascular large B-cell lymphoma involving central nervous system
dc.contributor.authorLee, J
dc.contributor.authorTan, S.Y
dc.contributor.authorTan, L.H.C
dc.contributor.authorLee, H.Y
dc.contributor.authorChuah, K.L
dc.contributor.authorTang, T
dc.contributor.authorQuek, R
dc.contributor.authorTay, K
dc.contributor.authorTao, M
dc.contributor.authorLim, S.T
dc.contributor.authorFarid, M
dc.date.accessioned2020-10-28T07:06:35Z
dc.date.available2020-10-28T07:06:35Z
dc.date.issued2014
dc.identifier.citationLee, J, Tan, S.Y, Tan, L.H.C, Lee, H.Y, Chuah, K.L, Tang, T, Quek, R, Tay, K, Tao, M, Lim, S.T, Farid, M (2014). One patient, two uncommon B-cell neoplasms: Solitary plasmacytoma following complete remission from intravascular large B-cell lymphoma involving central nervous system. Case Reports in Medicine 2014 : 620423. ScholarBank@NUS Repository. https://doi.org/10.1155/2014/620423
dc.identifier.issn16879627
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/181762
dc.description.abstractSecond lymphoid neoplasms are an uncommon but recognized feature of non-Hodgkin's lymphomas, putatively arising secondary to common genetic or environmental risk factors. Previous limited evaluations of clonal relatedness between successive mature B-cell malignancies have yielded mixed results. We describe the case of a man with intravascular large B-cell lymphoma involving the central nervous system who went into clinical remission following immunochemotherapy and brain radiation, only to relapse 2 years later with a plasmacytoma of bone causing cauda equina syndrome. The plasmacytoma stained strongly for the cell cycle regulator cyclin D1 on immunohistochemistry, while the original intravascular large cell lymphoma was negative, a disparity providing no support for clonal identity between the 2 neoplasms. Continued efforts atcataloging and evaluating unique associations of B-cell malignancies are critical to improving understanding of overarching disease biology in B-cell malignancies. © 2014 Joycelyn Lee et al.
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceUnpaywall 20201031
dc.subjectCD20 antigen
dc.subjectcyclin D1
dc.subjectcyclophosphamide
dc.subjectdoxorubicin
dc.subjectimmunoglobulin lambda chain
dc.subjectKi 67 antigen
dc.subjectlactate dehydrogenase
dc.subjectmethotrexate
dc.subjectprednisolone
dc.subjectrituximab
dc.subjectvincristine
dc.subjectadult
dc.subjectantibody labeling
dc.subjectarticle
dc.subjectbone cancer
dc.subjectbone marrow biopsy
dc.subjectbone plasmacytoma
dc.subjectbrain edema
dc.subjectbrain radiation
dc.subjectcancer chemotherapy
dc.subjectcancer combination chemotherapy
dc.subjectcancer grading
dc.subjectcancer immunotherapy
dc.subjectcancer radiotherapy
dc.subjectcancer recurrence
dc.subjectcancer regression
dc.subjectcase report
dc.subjectcauda equina syndrome
dc.subjectconfusion
dc.subjectcorticosteroid therapy
dc.subjectdrug megadose
dc.subjectflaccid paralysis
dc.subjectgerminal center
dc.subjectheadache
dc.subjecthemisphere
dc.subjecthospital infection
dc.subjecthuman
dc.subjecthuman tissue
dc.subjectimmunochemotherapy
dc.subjectimmunohistochemistry
dc.subjectimmunosuppressive treatment
dc.subjectin situ hybridization
dc.subjectInternational Prognostic Index
dc.subjectlactate dehydrogenase blood level
dc.subjectlarge cell lymphoma
dc.subjectlobectomy
dc.subjectmale
dc.subjectmiddle aged
dc.subjectmultimodality cancer therapy
dc.subjectneuroimaging
dc.subjectnosocomial pneumonia
dc.subjectnuclear magnetic resonance imaging
dc.subjectoccipital lobe
dc.subjectoccipital lobotomy
dc.subjectparaplegia
dc.subjectphenotype
dc.subjectplasmacytoma
dc.subjectpneumonia
dc.subjectpons
dc.subjectpriority journal
dc.subjectradiation dose fractionation
dc.subjectseizure
dc.typeArticle
dc.contributor.departmentDEPT OF PATHOLOGY
dc.contributor.departmentDUKE-NUS MEDICAL SCHOOL
dc.description.doi10.1155/2014/620423
dc.description.sourcetitleCase Reports in Medicine
dc.description.volume2014
dc.description.page620423
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