Please use this identifier to cite or link to this item: https://doi.org/10.3389/fncir.2013.00160
Title: Next-generation transgenic mice for optogenetic analysis of neural circuits
Authors: Asrican, B
Augustine, G.J 
Berglund, K
Chen, S
Chow, N
Deisseroth, K
Feng, G
Gloss, B
Hira, R
Hoffmann, C
Kasai, H
Katarya, M
Kim, J
Kudolo, J
Lee, L.M
Lo, S.Q 
Mancuso, J
Matsuzaki, M
Nakajima, R
Qiu, L
Tan, G
Tang, Y
Ting, J.T
Tsuda, S
Wen, L
Zhang, X
Zhao, S
Keywords: channelrhodopsin
halorhodopsin
rhodopsin
unclassified drug
rhodopsin
channelrhodopsin
amygdaloid nucleus
animal cell
article
brain cortex
brain function
brain mapping
cerebellum
connectome
controlled study
fluorescence
gene expression
genetic analysis
hippocampus
in vitro study
in vivo study
limb movement
medulla oblongata
mesencephalon
molecular genetics
mouse
nonhuman
olfactory bulb
optogenetics
photoinhibition
photostimulation
pons
promoter region
septum pellucidum
thalamus
transgenic mouse
action potential
animal
genetics
nerve cell
nerve cell network
nerve tract
optogenetics
physiology
procedures
transgenic mouse
cortex
methodology
nerve cell
nerve cell network
Action Potentials
Animals
Mice
Mice, Transgenic
Nerve Net
Neural Pathways
Neurons
Optogenetics
Rhodopsin
cerebellum
channelrhodopsin
cortex
hippocampus
optogenetics
photoinhibition
photostimulation
pons
Action Potentials
Animals
Mice
Mice, Transgenic
Nerve Net
Neural Pathways
Neurons
Optogenetics
Rhodopsin
Issue Date: 2013
Citation: Asrican, B, Augustine, G.J, Berglund, K, Chen, S, Chow, N, Deisseroth, K, Feng, G, Gloss, B, Hira, R, Hoffmann, C, Kasai, H, Katarya, M, Kim, J, Kudolo, J, Lee, L.M, Lo, S.Q, Mancuso, J, Matsuzaki, M, Nakajima, R, Qiu, L, Tan, G, Tang, Y, Ting, J.T, Tsuda, S, Wen, L, Zhang, X, Zhao, S (2013). Next-generation transgenic mice for optogenetic analysis of neural circuits. Frontiers in Neural Circuits 7 (NOV) : 160. ScholarBank@NUS Repository. https://doi.org/10.3389/fncir.2013.00160
Rights: Attribution 4.0 International
Abstract: Here we characterize several new lines of transgenic mice useful for optogenetic analysis of brain circuit function. These mice express optogenetic probes, such as enhanced halorhodopsin or several different versions of channelrhodopsins, behind various neuron-specific promoters. These mice permit photoinhibition or photostimulation both in vitro and in vivo. Our results also reveal the important influence of fluorescent tags on optogenetic probe expression and function in transgenic mice. © 2013 Asrican, Augustine.
Source Title: Frontiers in Neural Circuits
URI: https://scholarbank.nus.edu.sg/handle/10635/181539
ISSN: 16625110
DOI: 10.3389/fncir.2013.00160
Rights: Attribution 4.0 International
Appears in Collections:Elements
Staff Publications

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
10_3389_fncir_2013_00160.pdf2.11 MBAdobe PDF

OPEN

NoneView/Download

SCOPUSTM   
Citations

51
checked on Sep 22, 2022

Page view(s)

160
checked on Sep 22, 2022

Google ScholarTM

Check

Altmetric


This item is licensed under a Creative Commons License Creative Commons