Please use this identifier to cite or link to this item: https://doi.org/10.1186/s12906-017-2075-7
Title: Acute effect of Clitoria ternatea flower beverage on glycemic response and antioxidant capacity in healthy subjects: A randomized crossover trial
Authors: Chusak, C
Thilavech, T
Henry, C.J 
Adisakwattana, S
Keywords: Clitoria ternatea extract
glucose
insulin
malonaldehyde
plant extract
sucrose
thiol
unclassified drug
uric acid
water
antioxidant
insulin
plant extract
adult
antidiabetic activity
antioxidant activity
antioxidant assay
Article
beverage
body mass
Clitoria ternatea
controlled study
crossover procedure
ferric reducing antioxidant power assay
flower
glucose blood level
human
human experiment
insulin blood level
lipid peroxidation
male
normal human
oxygen radical absorbance capacity
randomized controlled trial
blood
chemistry
Clitoria
drug effects
postprandial state
young adult
Adult
Antioxidants
Beverages
Blood Glucose
Clitoria
Cross-Over Studies
Humans
Insulin
Lipid Peroxidation
Male
Plant Extracts
Postprandial Period
Young Adult
Issue Date: 2018
Citation: Chusak, C, Thilavech, T, Henry, C.J, Adisakwattana, S (2018). Acute effect of Clitoria ternatea flower beverage on glycemic response and antioxidant capacity in healthy subjects: A randomized crossover trial. BMC Complementary and Alternative Medicine 18 (1) : 6. ScholarBank@NUS Repository. https://doi.org/10.1186/s12906-017-2075-7
Rights: Attribution 4.0 International
Abstract: Background: Clitoria ternatea L., a natural food-colorant containing anthocyanin, demonstrated antioxidant and antihyperglycemic activity. The aim of this study was to determine the effects of Clitoria ternatea flower extract (CTE) on postprandial plasma glycemia response and antioxidant status in healthy men. Methods: In a randomized, crossover study, 15 healthy men (ages 22.53 ± 0.30 years; with body mass index of 21.57 ± 0.54 kg/m2) consumed five beverages: (1) 50 g sucrose in 400 mL water; (2) 1 g CTE in 400 mL of water; (3) 2 g CTE in 400 mL of water; (4) 50 g sucrose and 1 g CTE in 400 mL of water; and (5) 50 g sucrose and 2 g CTE in 400 mL of water. Incremental postprandial plasma glucose, insulin, uric acid, antioxidant capacities and lipid peroxidation were measured during 3 h of administration. Results: After 30 min ingestion, the postprandial plasma glucose and insulin levels were suppressed when consuming sucrose plus 1 g and 2 g CTE. In addition, consumption of CTE alone did not alter plasma glucose and insulin concentration in the fasting state. The significant increase in plasma antioxidant capacity (ferric reducing ability of plasma (FRAP), oxygen radical absorbance capacity (ORAC), trolox equivalent antioxidant capacity (TEAC), and protein thiol) and the decrease in malondialdehyde (MDA) level were observed in the subjects who received 1 g and 2 g CTE. Furthermore, consumption of CTE protected sucrose-induced reduction in ORAC and TEAC and increase in plasma MDA. Conclusions: These findings suggest that an acute ingestion of CTE increases plasma antioxidant capacity without hypoglycemia in the fasting state. It also improves postprandial glucose, insulin and antioxidant status when consumed with sucrose. Trial registration: Thai Clinical Trials Registry: TCTR20170609003. Registered 09 September 2017. 'retrospectively registered'. © 2018 The Author(s).
Source Title: BMC Complementary and Alternative Medicine
URI: https://scholarbank.nus.edu.sg/handle/10635/181223
ISSN: 14726882
DOI: 10.1186/s12906-017-2075-7
Rights: Attribution 4.0 International
Appears in Collections:Elements
Staff Publications

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
10_1186_s12906-017-2075-7.pdf1.03 MBAdobe PDF

OPEN

NoneView/Download

Google ScholarTM

Check

Altmetric


This item is licensed under a Creative Commons License Creative Commons