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Title: Cluster of SARS among Medical Students Exposed to Single Patient, Hong Kong
Authors: Wong, T.-W
Lee, C.-K
Tam, W 
Lau, J.T.-F
Yu, T.-S
Lui, S.-F
Chan, P.K.S
Li, Y
Bresee, J.S
Sung, J.J.Y
Parashar, U.D
Keywords: aerosol
clinical feature
cohort analysis
disease transmission
Hong Kong
infection risk
major clinical study
medical student
occupational exposure
retrospective study
severe acute respiratory syndrome
Issue Date: 2004
Publisher: Centers for Disease Control and Prevention (CDC)
Citation: Wong, T.-W, Lee, C.-K, Tam, W, Lau, J.T.-F, Yu, T.-S, Lui, S.-F, Chan, P.K.S, Li, Y, Bresee, J.S, Sung, J.J.Y, Parashar, U.D (2004). Cluster of SARS among Medical Students Exposed to Single Patient, Hong Kong. Emerging Infectious Diseases 10 (2) : 269-276. ScholarBank@NUS Repository.
Rights: Attribution 4.0 International
Abstract: We studied transmission patterns of severe acute respiratory syndrome (SARS) among medical students exposed exclusively to the first SARS patient in the Prince of Wales Hospital in Hong Kong, before his illness was recognized. We conducted a retrospective cohort study of 66 medical students who visited the index patient's ward, including 16 students with SARS and 50 healthy students. The risk of contracting SARS was sevenfold greater among students who definitely visited the index case's cubicle than in those who did not (10/27 [41%] versus 1/20 [5%], relative risk 7.4; 95% confidence interval 1.0 to 53.3). Illness rates increased directly with proximity of exposure to the index case. However, four of eight students who were in the same cubicle, but were not within 1 m of the index case-patient, contracted SARS. Proximity to the index case-patient was associated with transmission, which is consistent with droplet spread. Transmission through fomites or small aerosols cannot be ruled out.
Source Title: Emerging Infectious Diseases
ISSN: 10806040
DOI: 10.3201/eid1002.030452
Rights: Attribution 4.0 International
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