Please use this identifier to cite or link to this item: https://doi.org/10.1007/s10633-018-9645-y
Title: ISCEV extended protocol for the photopic On–Off ERG
Authors: Sustar, M
Holder, G.E 
Kremers, J
Barnes, C.S
Lei, B
Khan, N.W
Robson, A.G
Keywords: quinine
A wave
Article
B wave
disease association
Duchenne muscular dystrophy
electroretinography
human
medical society
melanoma
neuronal ceroid lipofuscinosis
night blindness
photostimulation
phototransduction
priority journal
retina cone
retina disease
retina dystrophy
retina rod
retinoschisis
spinocerebellar degeneration
stimulus response
clinical protocol
color vision
electrophysiology
electroretinography
organization and management
pathophysiology
physiology
retina
standards
Clinical Protocols
Color Vision
Electrophysiology
Electroretinography
Humans
Photic Stimulation
Retina
Retinal Cone Photoreceptor Cells
Retinal Dystrophies
Societies, Medical
Issue Date: 2018
Publisher: Springer Heidelberg
Citation: Sustar, M, Holder, G.E, Kremers, J, Barnes, C.S, Lei, B, Khan, N.W, Robson, A.G (2018). ISCEV extended protocol for the photopic On–Off ERG. Documenta Ophthalmologica 136 (3) : 199-206. ScholarBank@NUS Repository. https://doi.org/10.1007/s10633-018-9645-y
Rights: Attribution 4.0 International
Abstract: The International Society for Clinical Electrophysiology of Vision (ISCEV) standard for full-field electroretinography (ERG) describes a minimum procedure, but encourages more extensive testing. This ISCEV extended protocol describes an extension to the ERG standard, namely the photopic On–Off ERG, and outlines common clinical applications. A light stimulus duration of 150–200 ms is used in the presence of a rod-suppressing background to elicit cone-driven On- and Off-system ERG components. The On-response occurs after the stimulus onset and has a negative a-wave and positive b-wave. The Off d-wave is a positive component evoked by stimulus offset. Common diagnoses that may benefit from additional photopic On–Off ERG testing include retinal dystrophies and retinal disorders that cause dysfunction at a level that is post-phototransduction or post-receptoral. On–Off ERGs assess the relative involvement of On- and Off-systems and may be of use in the diagnosis of disorders such as complete and incomplete congenital stationary night blindness (complete and incomplete CSNB), melanoma-associated retinopathy, and some forms of autoimmune retinopathy. The photopic On–Off ERGs may also be useful in X-linked retinoschisis, Batten disease, Duchenne muscular dystrophy, spinocerebellar degeneration, quinine toxicity, and other retinal disorders. © 2018, The Author(s).
Source Title: Documenta Ophthalmologica
URI: https://scholarbank.nus.edu.sg/handle/10635/179034
ISSN: 00124486
DOI: 10.1007/s10633-018-9645-y
Rights: Attribution 4.0 International
Appears in Collections:Elements
Staff Publications

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
10_1007_s10633-018-9645-y.pdf420.5 kBAdobe PDF

OPEN

NoneView/Download

SCOPUSTM   
Citations

12
checked on Nov 21, 2020

Page view(s)

20
checked on Nov 26, 2020

Google ScholarTM

Check

Altmetric


This item is licensed under a Creative Commons License Creative Commons