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https://doi.org/10.3390/toxins8120360
Title: | Snake genome sequencing: Results and future prospects | Authors: | Kerkkamp, H.M.I Kini, R.M Pospelov, A.S Vonk, F.J Henkel, C.V Richardson, M.K |
Keywords: | nerve growth factor toxin gene duplication gene expression genome analysis molecular phylogeny Naja nonhuman Review snake transposon animal genetics genome nucleotide repeat snake Animals Genome Repetitive Sequences, Nucleic Acid Snakes Toxins, Biological |
Issue Date: | 2016 | Citation: | Kerkkamp, H.M.I, Kini, R.M, Pospelov, A.S, Vonk, F.J, Henkel, C.V, Richardson, M.K (2016). Snake genome sequencing: Results and future prospects. Toxins 8 (12) : 360. ScholarBank@NUS Repository. https://doi.org/10.3390/toxins8120360 | Rights: | Attribution 4.0 International | Abstract: | Snake genome sequencing is in its infancy—very much behind the progress made in sequencing the genomes of humans, model organisms and pathogens relevant to biomedical research, and agricultural species. We provide here an overview of some of the snake genome projects in progress, and discuss the biological findings, with special emphasis on toxinology, from the small number of draft snake genomes already published. We discuss the future of snake genomics, pointing out that new sequencing technologies will help overcome the problem of repetitive sequences in assembling snake genomes. Genome sequences are also likely to be valuable in examining the clustering of toxin genes on the chromosomes, in designing recombinant antivenoms and in studying the epigenetic regulation of toxin gene expression. © 2016 by the author; licensee MDPI, Basel, Switzerland. | Source Title: | Toxins | URI: | https://scholarbank.nus.edu.sg/handle/10635/178750 | ISSN: | 20726651 | DOI: | 10.3390/toxins8120360 | Rights: | Attribution 4.0 International |
Appears in Collections: | Elements Staff Publications |
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