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https://doi.org/10.3390/nu10010010
Title: | Association between malnutrition and 28-day mortality and intensive care length-of-stay in the critically ill: A prospective cohort study | Authors: | Lew, C.C.H Wong, G.J.Y Cheung, K.P Chua, A.P Chong, M.F.F Miller, M |
Keywords: | adult analytical parameters APACHE Article artificial ventilation Charlson morbidity index clinical evaluation cohort analysis controlled study critically ill patient disease association electronic medical record evaluation and follow up female Global Assessment of Functioning health care quality health practitioner high dependency unit hospital admission hospitalization human intensive care unit length of stay major clinical study male malnutrition middle aged mortality multivariate analysis nutritional assessment nutritional status observational study prospective study resuscitation tertiary care center young adult aged chi square distribution critical illness hospital mortality malnutrition nutritional status odds ratio pathophysiology risk factor Singapore statistical model time factor very elderly Adult Aged Aged, 80 and over Chi-Square Distribution Critical Illness Female Hospital Mortality Humans Intensive Care Units Length of Stay Linear Models Logistic Models Male Malnutrition Middle Aged Multivariate Analysis Nutrition Assessment Nutritional Status Odds Ratio Prospective Studies Risk Factors Singapore Tertiary Care Centers Time Factors |
Issue Date: | 2018 | Citation: | Lew, C.C.H, Wong, G.J.Y, Cheung, K.P, Chua, A.P, Chong, M.F.F, Miller, M (2018). Association between malnutrition and 28-day mortality and intensive care length-of-stay in the critically ill: A prospective cohort study. Nutrients 10 (1) : 10. ScholarBank@NUS Repository. https://doi.org/10.3390/nu10010010 | Rights: | Attribution 4.0 International | Abstract: | There is limited evidence for the association between malnutrition and mortality as well as Intensive Care Unit length-of-stay (ICU-LOS) in critically ill patients. We aimed to examine the aforementioned associations by conducting a prospective cohort study in an ICU of a Singapore tertiary hospital. Between August 2015 and October 2016, all adult patients with ? 24 h of ICU-LOS were included. The 7-point Subjective Global Assessment (7-point SGA) was used to determine patients’ nutritional status within 48 h of ICU admission. Multivariable regressions were conducted in two ways: (1) presence versus absence of malnutrition, and (2) dose-dependent association for each 1-point decrease in the 7-point SGA. There were 439 patients of which 28.0% were malnourished, and the 28-day mortality rate was 28.0%. Malnutrition was associated with an increased risk of 28-day mortality (adjusted Relative Risk 1.33 (95% Confidence Interval: 1.05-1.69)), and this risk increased with a greater degree of malnutrition (adjusted Relative Risk 1.08 (95% Confidence Interval: 1.00-1.16) for each 1-point decrease in the 7-point SGA). No significant association was found between malnutrition and ICU-LOS. The results of this study indicated a clear association between malnutrition and higher 28-day mortality in critically ill patients. The association between malnutrition and ICU-LOS could not be replicated and hence requires further evaluation. © 2017 by the authors. Licensee MDPI, Basel, Switzerland. | Source Title: | Nutrients | URI: | https://scholarbank.nus.edu.sg/handle/10635/178281 | ISSN: | 20726643 | DOI: | 10.3390/nu10010010 | Rights: | Attribution 4.0 International |
Appears in Collections: | Elements Staff Publications |
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