Please use this identifier to cite or link to this item: https://doi.org/10.3390/nu10010010
Title: Association between malnutrition and 28-day mortality and intensive care length-of-stay in the critically ill: A prospective cohort study
Authors: Lew, C.C.H
Wong, G.J.Y
Cheung, K.P
Chua, A.P
Chong, M.F.F 
Miller, M
Keywords: adult
analytical parameters
APACHE
Article
artificial ventilation
Charlson morbidity index
clinical evaluation
cohort analysis
controlled study
critically ill patient
disease association
electronic medical record
evaluation and follow up
female
Global Assessment of Functioning
health care quality
health practitioner
high dependency unit
hospital admission
hospitalization
human
intensive care unit
length of stay
major clinical study
male
malnutrition
middle aged
mortality
multivariate analysis
nutritional assessment
nutritional status
observational study
prospective study
resuscitation
tertiary care center
young adult
aged
chi square distribution
critical illness
hospital mortality
malnutrition
nutritional status
odds ratio
pathophysiology
risk factor
Singapore
statistical model
time factor
very elderly
Adult
Aged
Aged, 80 and over
Chi-Square Distribution
Critical Illness
Female
Hospital Mortality
Humans
Intensive Care Units
Length of Stay
Linear Models
Logistic Models
Male
Malnutrition
Middle Aged
Multivariate Analysis
Nutrition Assessment
Nutritional Status
Odds Ratio
Prospective Studies
Risk Factors
Singapore
Tertiary Care Centers
Time Factors
Issue Date: 2018
Citation: Lew, C.C.H, Wong, G.J.Y, Cheung, K.P, Chua, A.P, Chong, M.F.F, Miller, M (2018). Association between malnutrition and 28-day mortality and intensive care length-of-stay in the critically ill: A prospective cohort study. Nutrients 10 (1) : 10. ScholarBank@NUS Repository. https://doi.org/10.3390/nu10010010
Rights: Attribution 4.0 International
Abstract: There is limited evidence for the association between malnutrition and mortality as well as Intensive Care Unit length-of-stay (ICU-LOS) in critically ill patients. We aimed to examine the aforementioned associations by conducting a prospective cohort study in an ICU of a Singapore tertiary hospital. Between August 2015 and October 2016, all adult patients with ? 24 h of ICU-LOS were included. The 7-point Subjective Global Assessment (7-point SGA) was used to determine patients’ nutritional status within 48 h of ICU admission. Multivariable regressions were conducted in two ways: (1) presence versus absence of malnutrition, and (2) dose-dependent association for each 1-point decrease in the 7-point SGA. There were 439 patients of which 28.0% were malnourished, and the 28-day mortality rate was 28.0%. Malnutrition was associated with an increased risk of 28-day mortality (adjusted Relative Risk 1.33 (95% Confidence Interval: 1.05-1.69)), and this risk increased with a greater degree of malnutrition (adjusted Relative Risk 1.08 (95% Confidence Interval: 1.00-1.16) for each 1-point decrease in the 7-point SGA). No significant association was found between malnutrition and ICU-LOS. The results of this study indicated a clear association between malnutrition and higher 28-day mortality in critically ill patients. The association between malnutrition and ICU-LOS could not be replicated and hence requires further evaluation. © 2017 by the authors. Licensee MDPI, Basel, Switzerland.
Source Title: Nutrients
URI: https://scholarbank.nus.edu.sg/handle/10635/178281
ISSN: 20726643
DOI: 10.3390/nu10010010
Rights: Attribution 4.0 International
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