Please use this identifier to cite or link to this item: https://doi.org/10.3390/nu11020280
Title: Association of total and trimester-specific gestational weight gain rate with early infancy weight status: A prospective birth cohort study in China
Authors: Hu, J
Aris, I.M 
Oken, E
Ma, Y
Ding, N
Gao, M
Wei, X
Wen, D
Keywords: article
body mass
boy
child growth
China
cohort analysis
controlled study
female
gestational weight gain
human
infancy
infant
linear regression analysis
male
progeny
prospective study
third trimester pregnancy
China
clinical trial
cohort analysis
multicenter study
newborn
pregnancy
prospective study
China
Cohort Studies
Female
Gestational Weight Gain
Humans
Infant
Infant, Newborn
Male
Pregnancy
Pregnancy Trimesters
Prospective Studies
Issue Date: 2019
Citation: Hu, J, Aris, I.M, Oken, E, Ma, Y, Ding, N, Gao, M, Wei, X, Wen, D (2019). Association of total and trimester-specific gestational weight gain rate with early infancy weight status: A prospective birth cohort study in China. Nutrients 11 (2) : 280. ScholarBank@NUS Repository. https://doi.org/10.3390/nu11020280
Rights: Attribution 4.0 International
Abstract: Studies to examine the associations of gestational weight gain (GWG) with offspring weight status during infancy are needed, especially among Asian populations. We examined 801 mother–infant pairs from a prospective cohort study in China to assess the associations of total and trimester-specific GWG with early infant weight status. We used linear mixed effects models and linear regression models to examine the longitudinal and time-point associations of GWG rate (kg/week) with infant growth measures (z-scores of body-mass-index (BMIZ), weight-for-age (WFAZ) and length-for-age (LFAZ)) at birth, 1, 3, and 6 months. Greater total GWG rate was associated with higher BMIZ (?:1.34 SD units (95% CI: 0.84, 1.83) per 1 kg/week increase in GWG) and higher WFAZ (?:1.18 SD units (95% CI: 1.01, 2.28)) across the first 6 months of life. GWG rate in the first two trimesters but not in the third trimester was positively associated with infant BMIZ. The association between GWG rate and infant BMIZ was significant at all timepoints and more pronounced in normal weight women and among male infants. In conclusion, greater GWG rate is positively associated with offspring BMIZ in the first 6 months of life, the association is mostly driven by GWG in the first two trimesters. © 2019 by the authors. Licensee MDPI, Basel, Switzerland.
Source Title: Nutrients
URI: https://scholarbank.nus.edu.sg/handle/10635/177801
ISSN: 20726643
DOI: 10.3390/nu11020280
Rights: Attribution 4.0 International
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