Please use this identifier to cite or link to this item: https://doi.org/10.3390/ijerph15081705
Title: Effects of horticultural therapy on asian older adults: A randomized controlled trial
Authors: Ng, K.S.T
Sia, A
Ng, M.K.W
Tan, C.T.Y
Chan, H.Y 
Tan, C.H 
Rawtaer, I 
Feng, L 
Mahendran, R 
Larbi, A
Kua, E.H 
Ho, R.C.M 
Keywords: brain derived neurotrophic factor
C reactive protein
glycoprotein
glycoprotein 130
interleukin 1beta
interleukin 6
prasterone
RANTES
stromal cell derived factor 1
stromal cell derived factor 1alpha
unclassified drug
brain derived neurotrophic factor
hydrocortisone
interleukin derivative
prasterone
stromal cell derived factor 1
biomarker
elderly population
endocrine system
health status
horticulture
immune system
life satisfaction
plasma
adult
anxiety
Article
Asian
central nervous system
clinical effectiveness
cognition
controlled study
depression
female
gene expression regulation
hematopoietic system
horticultural therapy
human
immune system
immunomodulation
immunoregulation
life satisfaction
male
pleiotropy
protein blood level
protein secretion
psychological well-being
randomized controlled trial
social interaction
social psychology
aged
Asian continental ancestry group
biosynthesis
brain
depression
horticultural therapy
human relation
mental health
metabolism
middle aged
procedures
Aged
Anxiety
Asian Continental Ancestry Group
Brain
Brain-Derived Neurotrophic Factor
Chemokine CXCL12
Cognition
Dehydroepiandrosterone
Depression
Female
Horticultural Therapy
Humans
Hydrocortisone
Interleukins
Interpersonal Relations
Male
Mental Health
Middle Aged
Issue Date: 2018
Citation: Ng, K.S.T, Sia, A, Ng, M.K.W, Tan, C.T.Y, Chan, H.Y, Tan, C.H, Rawtaer, I, Feng, L, Mahendran, R, Larbi, A, Kua, E.H, Ho, R.C.M (2018). Effects of horticultural therapy on asian older adults: A randomized controlled trial. International Journal of Environmental Research and Public Health 15 (8) : 1705. ScholarBank@NUS Repository. https://doi.org/10.3390/ijerph15081705
Abstract: The effect of horticultural therapy (HT) on immune and endocrine biomarkers remains largely unknown. We designed a waitlist-control randomized controlled trial to investigate the effectiveness of HT in improving mental well-being and modulating biomarker levels. A total of 59 older adults was recruited, with 29 randomly assigned to the HT intervention and 30 to the waitlist control group. The participants attended weekly intervention sessions for the first 3 months and monthly sessions for the subsequent 3 months. Biological and psychosocial data were collected. Biomarkers included IL-1β, IL-6, sgp-130, CXCL12/SDF-1α, CCL-5/RANTES, BDNF (brain-derived neurotrophic factor), hs-CRP, cortisol and DHEA (dehydroepiandrosterone). Psychosocial measures examined cognitive functions, depression, anxiety, psychological well-being, social connectedness and satisfaction with life. A significant reduction in plasma IL-6 level (p = 0.02) was observed in the HT intervention group. For the waitlist control group, significant reductions in plasma CXCL12 (SDF-1α) (p = 0.003), CXCL5 (RANTES) (p = 0.05) and BDNF (p = 0.003) were observed. A significant improvement in social connectedness was also observed in the HT group (p = 0.01). Conclusion: HT, in reducing plasma IL-6, may prevent inflammatory disorders and through maintaining plasma CXCL12 (SDF-1α), may maintain hematopoietic support to the brain. HT may be applied in communal gardening to enhance the well-being of older adults. © 2018 by the authors.
Source Title: International Journal of Environmental Research and Public Health
URI: https://scholarbank.nus.edu.sg/handle/10635/176201
ISSN: 1661-7827
DOI: 10.3390/ijerph15081705
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