Please use this identifier to cite or link to this item: https://doi.org/10.3389/fphys.2018.00742
Title: Application of patient-specific computational fluid dynamics in coronary and intra-cardiac flow simulations: Challenges and opportunities
Authors: Zhong, L 
Zhang, J.-M 
Su, B
Tan, R.S 
Allen, J.C 
Kassab, G.S
Keywords: adult
blood flow
clinical trial (topic)
computational fluid dynamics
controlled study
diagnosis
diagnostic imaging
geometry
heart
human
image segmentation
market
review
simulation
Issue Date: 2018
Citation: Zhong, L, Zhang, J.-M, Su, B, Tan, R.S, Allen, J.C, Kassab, G.S (2018). Application of patient-specific computational fluid dynamics in coronary and intra-cardiac flow simulations: Challenges and opportunities. Frontiers in Physiology 9 (JUN) : 742. ScholarBank@NUS Repository. https://doi.org/10.3389/fphys.2018.00742
Abstract: The emergence of new cardiac diagnostics and therapeutics of the heart has given rise to the challenging field of virtual design and testing of technologies in a patient-specific environment. Given the recent advances in medical imaging, computational power and mathematical algorithms, patient-specific cardiac models can be produced from cardiac images faster, and more efficiently than ever before. The emergence of patient-specific computational fluid dynamics (CFD) has paved the way for the new field of computer-aided diagnostics. This article provides a review of CFD methods, challenges and opportunities in coronary and intra-cardiac flow simulations. It includes a review of market products and clinical trials. Key components of patient-specific CFD are covered briefly which include image segmentation, geometry reconstruction, mesh generation, fluid-structure interaction, and solver techniques. © 2018 Zhong, Zhang, Su, Tan, Allen and Kassab.
Source Title: Frontiers in Physiology
URI: https://scholarbank.nus.edu.sg/handle/10635/175378
ISSN: 1664-042X
DOI: 10.3389/fphys.2018.00742
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