1. ScholarBank@NUS
  2. 1. Staff
  3. Staff Publications
Please use this identifier to cite or link to this item: https://doi.org/10.1128/AAC.01298-17
DC FieldValue
dc.titleVancomycin and clarithromycin show synergy against Mycobacterium abscessus in vitro
dc.contributor.authorMukherjee, D
dc.contributor.authorWu, M.-L
dc.contributor.authorTeo, J.W.P
dc.contributor.authorDick, T
dc.date.accessioned2020-09-09T04:15:39Z
dc.date.available2020-09-09T04:15:39Z
dc.date.issued2017
dc.identifier.citationMukherjee, D, Wu, M.-L, Teo, J.W.P, Dick, T (2017). Vancomycin and clarithromycin show synergy against Mycobacterium abscessus in vitro. Antimicrobial Agents and Chemotherapy 61 (12) : e01298. ScholarBank@NUS Repository. https://doi.org/10.1128/AAC.01298-17
dc.identifier.issn0066-4804
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/175145
dc.description.abstractLung disease caused by Mycobacterium abscessus is increasing, and current clarithromycin-based treatment regimens are only moderately effective. Here, we determined the effect of clarithromycin-vancomycin combination against M. abscessus complex isolates in vitro. Synergy was found with a fractional inhibitory concentration index (FICI) score of ?0.5 and a 4- to 10-fold decrease in MIC. © 2017 Mukherjee et al.
dc.publisherAmerican Society for Microbiology
dc.sourceUnpaywall 20200831
dc.subjectclarithromycin
dc.subjectvancomycin
dc.subjectclarithromycin
dc.subjecttuberculostatic agent
dc.subjectvancomycin
dc.subjectantibacterial activity
dc.subjectArticle
dc.subjectbacterial growth
dc.subjectbacterium isolate
dc.subjectcontrolled study
dc.subjectdrug effect
dc.subjectdrug potentiation
dc.subjectfractional inhibitory concentration index
dc.subjectgene mutation
dc.subjectin vitro study
dc.subjectminimum inhibitory concentration
dc.subjectMycobacterium abscessus
dc.subjectMycobacterium massiliense
dc.subjectnonhuman
dc.subjectnucleotide sequence
dc.subjectpriority journal
dc.subjecttype strain
dc.subjectatypical mycobacteriosis
dc.subjectcombination drug therapy
dc.subjectdrug effect
dc.subjectdrug potentiation
dc.subjecthuman
dc.subjectlung disease
dc.subjectmicrobial sensitivity test
dc.subjectmicrobiology
dc.subjectMycobacterium abscessus
dc.subjecttreatment outcome
dc.subjectAntibiotics, Antitubercular
dc.subjectClarithromycin
dc.subjectDrug Synergism
dc.subjectDrug Therapy, Combination
dc.subjectHumans
dc.subjectLung Diseases
dc.subjectMicrobial Sensitivity Tests
dc.subjectMycobacterium abscessus
dc.subjectMycobacterium Infections, Nontuberculous
dc.subjectTreatment Outcome
dc.subjectVancomycin
dc.typeArticle
dc.contributor.departmentPHARMACY
dc.contributor.departmentDEPT OF MEDICINE
dc.contributor.departmentMICROBIOLOGY AND IMMUNOLOGY
dc.description.doi10.1128/AAC.01298-17
dc.description.sourcetitleAntimicrobial Agents and Chemotherapy
dc.description.volume61
dc.description.issue12
dc.description.pagee01298
dc.published.statePublished
Appears in Collections:Staff Publications
Elements

Show simple item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
10_1128_AAC_01298-17.pdf185.45 kBAdobe PDF

OPEN

NoneView/Download

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.