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Please use this identifier to cite or link to this item: https://doi.org/10.4269/ajtmh.15-0468
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dc.titleDissecting Japan's dengue outbreak in 2014
dc.contributor.authorQuam M.B.
dc.contributor.authorSessions O.
dc.contributor.authorKamaraj U.S.
dc.contributor.authorRocklöv J.
dc.contributor.authorWilder-Smith A.
dc.date.accessioned2020-09-08T03:55:45Z
dc.date.available2020-09-08T03:55:45Z
dc.date.issued2016
dc.identifier.citationQuam M.B., Sessions O., Kamaraj U.S., Rocklöv J., Wilder-Smith A. (2016). Dissecting Japan's dengue outbreak in 2014. American Journal of Tropical Medicine and Hygiene 94 (2) : 409-412. ScholarBank@NUS Repository. https://doi.org/10.4269/ajtmh.15-0468
dc.identifier.issn0002-9637
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/174666
dc.description.abstractDespite Japan's temperate climate, a dengue outbreak occurred in Tokyo for the first time in over 70 years in 2014. We dissected this dengue outbreak based on phylogenetic analysis, travel interconnectivity, and environmental drivers for dengue epidemics. Comparing the available dengue virus 1 (DENV1) E gene sequence from this outbreak with 3,282 unique DENV1 sequences in National Center for Biotechnology Information suggested that the DENV might have been imported from China, Indonesia, Singapore, or Vietnam. With travelers arriving into Japan, Guangzhou (China) may have been the source of DENV introduction, given that Guangzhou also reported a large-scale dengue outbreak in 2014. Coinciding with the 2014 outbreak, Tokyo's climate conditions permitted the amplification of Aedes vectors and the annual peak of vectorial capacity. Given suitable vectors and climate conditions in addition to increasing interconnectivity with endemic areas of Asia, Tokyo's 2014 outbreak did not come as a surprise and may foretell more to come. © 2016 by The American Society of Tropical Medicine and Hygiene.
dc.sourceUnpaywall 20200831
dc.subjectAedes aegypti
dc.subjectAedes albopictus
dc.subjectair temperature
dc.subjectArticle
dc.subjectautumn
dc.subjectChina
dc.subjectcircadian rhythm
dc.subjectclimate
dc.subjectdengue
dc.subjectDengue virus 1
dc.subjectepidemic
dc.subjectFourier transformation
dc.subjectgene sequence
dc.subjecthuman
dc.subjectincubation time
dc.subjectIndonesia
dc.subjectJapan
dc.subjectmortality rate
dc.subjectmultiple sequence alignment
dc.subjectphylogenetic tree
dc.subjectphylogeny
dc.subjectprecipitation
dc.subjectseasonal variation
dc.subjectsequence alignment
dc.subjectSingapore
dc.subjectspring
dc.subjectsummer
dc.subjecttravel
dc.subjectViet Nam
dc.subjectwinter
dc.subjectdengue
dc.subjectseason
dc.subjectDengue
dc.subjectHumans
dc.subjectJapan
dc.subjectPhylogeny
dc.subjectSeasons
dc.typeArticle
dc.contributor.departmentMEDICINE
dc.contributor.departmentDUKE-NUS MEDICAL SCHOOL
dc.description.doi10.4269/ajtmh.15-0468
dc.description.sourcetitleAmerican Journal of Tropical Medicine and Hygiene
dc.description.volume94
dc.description.issue2
dc.description.page409-412
dc.published.statePublished
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